CHEMBL2039 IC50
BioactivityChEMBL CHEMBL2039 IC50 bioactivity data
3417 compounds · Target: Amine oxidase [flavin-containing] B ( CHEMBL2039 ↗ ) · UniProt: P27338 ↗ · IC50
Amine oxidase [flavin-containing] B, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
7804 ↗ |
C#CCN(C)Cc1cccc(NC(=O)CCCCCCC(=O)NO)c1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
67.00×103 | IC50 | CHEMBL5171489 | ChEMBL ↗ |
|
9478 ↗ |
O=C(NO)c1ccc(CCCN2CCC(CN[C@H]3C[C@@H]3c3ccccc3)CC2)cc1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
6.60×103 | IC50 | CHEMBL4749146 | ChEMBL ↗ |
|
9875 ↗ |
O=C(NO)c1ccc(/C=C/c2ccnc(-c3ccccc3O)c2)cc1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
69.40×103 | IC50 | CHEMBL5075646 | ChEMBL ↗ |
|
11415 ↗ |
C#CCN(C)C1CCc2c(OC(=O)N(C)CC)cccc21
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
27.00 | IC50 | CHEMBL1190983 | ChEMBL ↗ |
|
11417 ↗ |
C#CCNC1CCc2c(OC(=O)N(C)CC)cccc21
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
830.00 | IC50 | CHEMBL1193656 | ChEMBL ↗ |
|
11448 ↗ |
O=C(c1ccc(OCCCc2c[nH]cn2)cc1)C1CC1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
2.00×103 | IC50 | CHEMBL14638 | ChEMBL ↗ |
|
11921 ↗ |
C#CCN(Cc1ccc(O)c2ncccc12)C(C#N)CCC1CCN(Cc2ccccc2)CC1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
11.80×103 | IC50 | CHEMBL3291019 | ChEMBL ↗ |
|
12028 ↗ |
C#CCN(C)Cc1cc2cc(OCCCC3CCN(Cc4ccccc4C)CC3)ccc2n1C
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
183.60 | IC50 | CHEMBL3407581 | ChEMBL ↗ |
|
12029 ↗ |
C#CCN(C)Cc1cc2cc(OCCCC3CCN(Cc4ccc(OC(=O)N(C)C)c5ncccc45)CC3)ccc2n1C
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
196.30 | IC50 | CHEMBL3407582 | ChEMBL ↗ |
|
12030 ↗ |
C#CCN(C)Cc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2[nH]1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
35.10×103 | IC50 | CHEMBL3407583 | ChEMBL ↗ |
|
12031 ↗ |
C#CCNCc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2[nH]1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
33.60×103 | IC50 | CHEMBL3407584 | ChEMBL ↗ |
|
12032 ↗ |
C=CCNCc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2[nH]1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
21.30×103 | IC50 | CHEMBL3407585 | ChEMBL ↗ |
|
12033 ↗ |
CCOC(=O)c1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2[nH]1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
1.00×103 | IC50 | CHEMBL3407586 | ChEMBL ↗ |
|
12034 ↗ |
OCc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2[nH]1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
13.50×103 | IC50 | CHEMBL3407587 | ChEMBL ↗ |
|
12038 ↗ |
Cc1c(Cl)c(=O)oc2cc(OCCN3CCN(CCCNc4c5c(nc6ccccc46)CCCC5)CC3)ccc12
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
700.00 | IC50 | CHEMBL3417299 | ChEMBL ↗ |
|
12039 ↗ |
Cc1c(C)c2ccc(OCCN3CCN(CCCNc4c5c(nc6ccccc46)CCCC5)CC3)cc2oc1=O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
240.00 | IC50 | CHEMBL3417300 | ChEMBL ↗ |
|
12044 ↗ |
Cc1c(C)c2ccc(OCCCCCCN(C)Cc3ccccc3)cc2oc1=O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
321.00 | IC50 | CHEMBL3586582 | ChEMBL ↗ |
|
12045 ↗ |
CN(Cc1ccccc1)Cc1ccc(COc2ccc3ccc(=O)oc3c2)cc1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
41.00 | IC50 | CHEMBL3586592 | ChEMBL ↗ |
|
12175 ↗ |
O=c1oc2cc(OCCNC3CCN(Cc4ccccc4)CC3)ccc2c2c1CCCC2
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
2.62×103 | IC50 | CHEMBL3763535 | ChEMBL ↗ |
|
12183 ↗ |
Cc1cc(=O)oc2cc(CNCCC3CCN(Cc4ccccc4)CC3)ccc12
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
40.50×103 | IC50 | CHEMBL3764211 | ChEMBL ↗ |
|
12189 ↗ |
Cc1c(C)c2ccc(OCCNC3CCN(Cc4ccccc4)CC3)cc2oc1=O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
23.40×103 | IC50 | CHEMBL3764609 | ChEMBL ↗ |
|
12192 ↗ |
Cc1c(Cl)c(=O)oc2cc(OCCNC3CCN(Cc4ccccc4)CC3)ccc12
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
14.70×103 | IC50 | CHEMBL3764762 | ChEMBL ↗ |
|
12198 ↗ |
O=c1cc(Cl)c2ccc(OCCNC3CCN(Cc4ccccc4)CC3)cc2o1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
33.90×103 | IC50 | CHEMBL3765293 | ChEMBL ↗ |
|
12300 ↗ |
C#CCN1CCC(CNS(=O)(=O)c2ccc3ccccc3c2)CC1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
53.90×103 | IC50 | CHEMBL3891772 | ChEMBL ↗ |
|
12331 ↗ |
C#CCN1CCCC(CNC(=O)c2ccc3ccccc3c2)C1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
59.29×103 | IC50 | CHEMBL3915915 | ChEMBL ↗ |
|
12371 ↗ |
COc1cc(/C=C/C(=O)Nc2cccc(CN(C)Cc3ccccc3)c2)ccc1O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
7.70×103 | IC50 | CHEMBL3945872 | ChEMBL ↗ |
|
12401 ↗ |
O=C(/C=C/c1ccc(O)cc1O)NCCC1CCN(Cc2ccccc2)CC1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
8.30×103 | IC50 | CHEMBL3965783 | ChEMBL ↗ |
|
12411 ↗ |
C#CCN1CCC(CNC(=O)c2ccc3ccccc3c2)CC1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
72.61×103 | IC50 | CHEMBL3980929 | ChEMBL ↗ |
|
12442 ↗ |
CCN(CCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1OC
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
4.70×103 | IC50 | CHEMBL4066908 | ChEMBL ↗ |
|
12452 ↗ |
CCN(CCCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1OC
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
9.40×103 | IC50 | CHEMBL4069776 | ChEMBL ↗ |
|
12466 ↗ |
C#CCN(CCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
2.60×103 | IC50 | CHEMBL4075667 | ChEMBL ↗ |
|
12511 ↗ |
CCN(CCCCCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1OC
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
11.70×103 | IC50 | CHEMBL4089264 | ChEMBL ↗ |
|
12517 ↗ |
CCN(CCCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
6.90×103 | IC50 | CHEMBL4091683 | ChEMBL ↗ |
|
12533 ↗ |
CCN(CCCCCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
12.20×103 | IC50 | CHEMBL4096963 | ChEMBL ↗ |
|
12676 ↗ |
CC(C)(C)c1cc(C(=O)CNCCC2CCN(Cc3ccccc3)CC2)cc(C(C)(C)C)c1O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
92.10×103 | IC50 | CHEMBL4279488 | ChEMBL ↗ |
|
12683 ↗ |
CC(C)(C)c1cc(/C=C/C(=O)NCCC2CCN(Cc3ccccc3)CC2)cc(C(C)(C)C)c1O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
8.50×103 | IC50 | CHEMBL4283390 | ChEMBL ↗ |
|
12690 ↗ |
Cc1ccc(NC(=O)c2coc3ccc(/C=C/C(=O)OCCN(C)C)cc3c2=O)cc1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
2.37×103 | IC50 | CHEMBL4284235 | ChEMBL ↗ |
|
12694 ↗ |
CN(C)CCOC(=O)/C=C/c1ccc2oc(C(=O)Nc3ccccc3)cc(=O)c2c1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
2.28×103 | IC50 | CHEMBL4285714 | ChEMBL ↗ |
|
12698 ↗ |
CN(C)CCOC(=O)/C=C/c1ccc2occ(C(=O)Nc3ccccc3)c(=O)c2c1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
630.00 | IC50 | CHEMBL4286556 | ChEMBL ↗ |
|
12701 ↗ |
O=C(NCCC1CCN(Cc2ccccc2)CC1)c1cc(=O)c2ccccc2o1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
20.03×103 | IC50 | CHEMBL4286799 | ChEMBL ↗ |
|
12721 ↗ |
O=C(NCCC1CCN(Cc2ccccc2)CC1)c1cc(=O)c2cc(O)ccc2[nH]1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
59.90×103 | IC50 | CHEMBL4294609 | ChEMBL ↗ |
|
12795 ↗ |
CCN(C)C(=O)Oc1cccc(/C=C/C(=O)c2ccccc2O)c1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
1.30×103 | IC50 | CHEMBL4466019 | ChEMBL ↗ |
|
12806 ↗ |
Cc1c(C)c2ccc(OCC3CCN(Cc4cccc(OCCCO)c4)CC3)cc2oc1=O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
780.00 | IC50 | CHEMBL4470448 | ChEMBL ↗ |
|
12818 ↗ |
O=C(/C=C/c1ccccc1)c1ccc(OCCCCCCN2CCCC2)cc1O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
12.70×103 | IC50 | CHEMBL4476091 | ChEMBL ↗ |
|
12862 ↗ |
O=C(/C=C/c1ccc(OCCCCCCN2CCCC2)cc1)c1ccc(OCCCCCCN2CCCC2)cc1O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
570.00 | IC50 | CHEMBL4537240 | ChEMBL ↗ |
|
12913 ↗ |
Cc1c(C)c2ccc(OCC3CCN(Cc4cccc(OCCCO[N+](=O)[O-])c4)CC3)cc2oc1=O
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
550.00 | IC50 | CHEMBL4578377 | ChEMBL ↗ |
|
12974 ↗ |
CCN(CC)C(=O)Oc1ccc(/C=C/C(=O)N2CCN(Cc3ccccc3)CC2)cc1OC
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
23.20×103 | IC50 | CHEMBL4740081 | ChEMBL ↗ |
|
12976 ↗ |
COc1cc(/C=C/C(=O)N2CCc3ccccc3C2)ccc1OC(=O)N(C)OC
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
6.80×103 | IC50 | CHEMBL4741070 | ChEMBL ↗ |
|
12992 ↗ |
COc1cc(/C=C/C(=O)N2CCc3ccccc3C2)ccc1OC(=O)N(c1ccccc1)c1ccccc1
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
12.20×103 | IC50 | CHEMBL4745075 | ChEMBL ↗ |
|
13005 ↗ |
CCN(C)C(=O)Oc1ccc(/C=C/C(=O)N2CCCCC2)cc1OC
|
CHEMBL2039 ↗
UniProt: P27338 ↗ |
16.30×103 | IC50 | CHEMBL4747710 | ChEMBL ↗ |