All Compounds

269462 entries

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ID SMILES Dataset Target Activity (nM) Type Link
1777 ↗
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)N[C@H]4CC[C@H](N5CCN(CC6CC6)CC5)CC4)cc3OC)nc2N1C(C)C
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		1.07×103 IC50 ChEMBL ↗
1778 ↗
CN1CCCC1=O
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		4.33×106 IC50 ChEMBL ↗
1779 ↗
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		290.00 IC50 ChEMBL ↗
1779 ↗
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1
CHEMBL1974 IC50 Receptor-type tyrosine-protein kinase FLT3 ↗
UniProt: P36888 ↗ 		20.00 IC50 ChEMBL ↗
1779 ↗
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1
CHEMBL2835 IC50 Tyrosine-protein kinase JAK1 ↗
UniProt: P23458 ↗ 		100.00 IC50 ChEMBL ↗
1780 ↗
COc1cc(C(=O)NCCOc2ccccc2)cc(OC)c1OC
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		6.60×103 IC50 ChEMBL ↗
1781 ↗
Cc1ccccc1NS(=O)(=O)c1ccc2c3c(cccc13)C(=O)N2C
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		15.53×103 IC50 ChEMBL ↗
1782 ↗
Oc1ccc(Cn2ccnc2)c2cccnc12
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		101.00 IC50 ChEMBL ↗
1783 ↗
COC(=O)C(CC(C)C)NC(=O)c1cc(OC)c(OC)c(OC)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		8.50×103 IC50 ChEMBL ↗
1784 ↗
O=c1cc(N2CCNCC2)oc2c(-c3ccccc3)cccc12
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		9.05×103 IC50 ChEMBL ↗
1785 ↗
COc1ccc(/C=C(\NC(=O)c2ccc(C)cc2)C(=O)NCCCn2ccnc2)cc1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		10.98×103 IC50 ChEMBL ↗
1786 ↗
Cc1ccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)cc1C
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		2.90×103 IC50 ChEMBL ↗
1787 ↗
CC(=O)N1CCCc2ccccc21
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		188.54×103 IC50 ChEMBL ↗
1788 ↗
Cc1cccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)c1C
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		2.50×103 IC50 ChEMBL ↗
1789 ↗
CCN(CC)S(=O)(=O)c1cc(NC(=O)CN2C(=O)NC(C)(c3ccccc3)C2=O)ccc1C
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		39.81×103 IC50 ChEMBL ↗
1790 ↗
CC(=O)c1cn(C)c(=O)c2ccccc12
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		71.00×103 IC50 ChEMBL ↗
1791 ↗
Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)c(C)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		2.51×103 IC50 ChEMBL ↗
1792 ↗
CCCOCc1ccc(O)c2ncccc12
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		2.10×103 IC50 ChEMBL ↗
1793 ↗
O=[N+]([O-])c1ccc(O)c2ncccc12
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		980.00 IC50 ChEMBL ↗
1794 ↗
Cc1ccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)cc1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		24.00×103 IC50 ChEMBL ↗
1795 ↗
COc1ccc(C2=NN(C(=O)CCCC(=O)O)C(c3cn(-c4ccccc4)nc3-c3ccccc3)C2)cc1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		5.36×103 IC50 ChEMBL ↗
1796 ↗
Oc1ccc(CNc2cccc(C(F)(F)F)c2)c2cccnc12
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		4.80×103 IC50 ChEMBL ↗
1797 ↗
CCN1C(=O)c2cccc3c(S(=O)(=O)Nc4ccccc4)ccc1c23
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		1.00×103 IC50 ChEMBL ↗
1798 ↗
Cn1c(=O)n(C)c2cc(C(N)=O)ccc21
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		79.43×103 IC50 ChEMBL ↗
1799 ↗
Cc1cc(C)c2ccc(NN)nc2c1O
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		18.00×103 IC50 ChEMBL ↗
1800 ↗
O=c1[nH]n(CC2COC3(CCCCC3)O2)c(=O)c2ccccc12
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		13.30×103 IC50 ChEMBL ↗
1801 ↗
CNS(=O)(=O)c1cc(-c2nn3c(C)nnc3c3ccccc23)ccc1C
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		2.00×103 IC50 ChEMBL ↗
1802 ↗
COc1ccccc1C(=O)Nc1cc2c(cc1N1CCCCC1)n(C)c(=O)n2C
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		3.16×103 IC50 ChEMBL ↗
1803 ↗
COc1cccc(C(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		15.82×103 IC50 ChEMBL ↗
1804 ↗
CN1C(=O)CC(c2ccccc2)Nc2ccccc21
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		7.50×103 IC50 ChEMBL ↗
1805 ↗
COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C)c1ccccc1C(=O)N2C
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		888.00 IC50 ChEMBL ↗
1806 ↗
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C)c1ccccc1C(=O)N2C
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		4.17×103 IC50 ChEMBL ↗
1807 ↗
CCc1nnc(NC(=O)C2(C)COC(c3ccccc3)OC2)s1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		69.23×103 IC50 ChEMBL ↗
1808 ↗
CCOC(=O)c1ncccc1NC(=O)CC(=O)Nc1cccnc1C(=O)OCC
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		2.87×103 IC50 ChEMBL ↗
1809 ↗
COCc1nnc(NC(=O)c2cc(OC)c(OC)c(OC)c2)s1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		11.00×103 IC50 ChEMBL ↗
1810 ↗
CCn1cnc2c1c(=O)[nH]c(=O)n2Cc1ccccc1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		12.59×103 IC50 ChEMBL ↗
1811 ↗
O=C(CN1CC(=O)Oc2ccccc21)OCC(=O)c1ccc(Br)cc1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		1.11×103 IC50 ChEMBL ↗
1812 ↗
O=C(CCNC(=O)c1ccccc1)Nc1ccc(Cl)c(S(=O)(=O)N2CCCCC2)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		39.81×103 IC50 ChEMBL ↗
1813 ↗
Cc1noc(C)c1-c1ccc2c(c1)CN(C)C(=O)N2
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		4.80×103 IC50 ChEMBL ↗
1814 ↗
CC(=O)c1cccc(-c2c(C)noc2C)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		24.60×103 IC50 ChEMBL ↗
1815 ↗
CCOc1cccc(-c2c(C)noc2C)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		23.20×103 IC50 ChEMBL ↗
1816 ↗
Cc1noc(C)c1-c1cccc(C(C)O)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		9.70×103 IC50 ChEMBL ↗
1817 ↗
CCOC(=O)c1cc(OCC)cc(-c2c(C)noc2C)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		7.70×103 IC50 ChEMBL ↗
1818 ↗
CCOc1cc(C(=O)O)cc(-c2c(C)noc2C)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		51.20×103 IC50 ChEMBL ↗
1819 ↗
CCOc1cc(C(C)=O)cc(-c2c(C)noc2C)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		7.50×103 IC50 ChEMBL ↗
1820 ↗
CCOc1cc(-c2c(C)noc2C)cc(C(C)O)c1
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		4.79×103 IC50 ChEMBL ↗
1821 ↗
O=c1cc(N2CCOCC2)oc2c(-c3cccc4c3sc3ccccc34)cccc12
CHEMBL1163125 IC50 Bromodomain-containing protein 4 ↗
UniProt: O60885 ↗ 		1.00×103 IC50 ChEMBL ↗
1821 ↗
O=c1cc(N2CCOCC2)oc2c(-c3cccc4c3sc3ccccc34)cccc12
CHEMBL240 IC50 Voltage-gated inwardly rectifying potassium channel KCNH2 ↗
UniProt: Q12809 ↗ 		14.00×103 IC50 ChEMBL ↗
1821 ↗
O=c1cc(N2CCOCC2)oc2c(-c3cccc4c3sc3ccccc34)cccc12
CHEMBL2842 IC50 Serine/threonine-protein kinase mTOR ↗
UniProt: P42345 ↗ 		2.40×103 IC50 ChEMBL ↗
1821 ↗
O=c1cc(N2CCOCC2)oc2c(-c3cccc4c3sc3ccccc34)cccc12
CHEMBL3130 IC50 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform ↗
UniProt: O00329 ↗ 		30.00 IC50 ChEMBL ↗