CHEMBL205 Ki

Bioactivity

ChEMBL CHEMBL205 Ki bioactivity data

5054 compounds · Target: Carbonic anhydrase 2 ( CHEMBL205 ↗ ) · UniProt: P00918 ↗ · Ki

Carbonic anhydrase 2, a molecular target studied in Homo sapiens.

Chemical Space

ID ↑	SMILES	Target	Activity (nM)	Type	Ref	Link
6570 ↗	O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23	CHEMBL205 ↗ UniProt: P00918 ↗	2.18×10³	Ki	CHEMBL6246	ChEMBL ↗
6574 ↗	Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1Nc1nccc(-c2cccnc2)n1	CHEMBL205 ↗ UniProt: P00918 ↗	30.20	Ki	CHEMBL941	ChEMBL ↗
6753 ↗	CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O	CHEMBL205 ↗ UniProt: P00918 ↗	1.16×10³	Ki	CHEMBL325041	ChEMBL ↗
11815 ↗	O=C1NS(=O)(=O)c2ccccc21	CHEMBL205 ↗ UniProt: P00918 ↗	5.97×10³	Ki	CHEMBL310671	ChEMBL ↗
13340 ↗	O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12	CHEMBL205 ↗ UniProt: P00918 ↗	2.54×10³	Ki	CHEMBL50	ChEMBL ↗
14315 ↗	Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	2.77×10³	Ki	CHEMBL165	ChEMBL ↗
15622 ↗	NS(=O)(=O)c1ccc(-c2nnc(-c3ccccc3)o2)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	7.48	Ki	CHEMBL4452583	ChEMBL ↗
17675 ↗	O=c1c(O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12	CHEMBL205 ↗ UniProt: P00918 ↗	9.53×10³	Ki	CHEMBL150	ChEMBL ↗
17678 ↗	O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12	CHEMBL205 ↗ UniProt: P00918 ↗	3.69×10³	Ki	CHEMBL151	ChEMBL ↗
17957 ↗	Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1	CHEMBL205 ↗ UniProt: P00918 ↗	4.10	Ki	CHEMBL255863	ChEMBL ↗
19946 ↗	O=c1cc(-c2ccccc2)oc2ccccc12	CHEMBL205 ↗ UniProt: P00918 ↗	8.76×10³	Ki	CHEMBL275638	ChEMBL ↗
19948 ↗	O=c1cc(-c2ccccc2)oc2cc(O)ccc12	CHEMBL205 ↗ UniProt: P00918 ↗	2.28×10³	Ki	CHEMBL276915	ChEMBL ↗
19961 ↗	NS(=O)(=O)Oc1ccc2c3c(c(=O)oc2c1)CCCCC3	CHEMBL205 ↗ UniProt: P00918 ↗	21.00	Ki	CHEMBL286738	ChEMBL ↗
20840 ↗	COc1cc(/C=C/C(=O)/C=C(O)/C=C/c2ccc(O)c(OC)c2)ccc1O	CHEMBL205 ↗ UniProt: P00918 ↗	380.00	Ki	CHEMBL116438	ChEMBL ↗
20908 ↗	O=C(O)/C=C/c1ccc(O)c(O)c1	CHEMBL205 ↗ UniProt: P00918 ↗	1.61×10³	Ki	CHEMBL145	ChEMBL ↗
24164 ↗	O=c1ccc2ccc(OCc3ccccc3)cc2o1	CHEMBL205 ↗ UniProt: P00918 ↗	50.30×10³	Ki	CHEMBL145781	ChEMBL ↗
25184 ↗	NS(=O)(=O)c1cccc(-c2nnc(-c3ccc(Cl)cc3)o2)c1	CHEMBL205 ↗ UniProt: P00918 ↗	608.00	Ki	CHEMBL4460034	ChEMBL ↗
25674 ↗	CCOC(=O)c1cc2ccc(OC)cc2oc1=O	CHEMBL205 ↗ UniProt: P00918 ↗	24.90×10³	Ki	CHEMBL568385	ChEMBL ↗
25679 ↗	Cc1ccc2oc(=O)c(C(=O)O)cc2c1	CHEMBL205 ↗ UniProt: P00918 ↗	9.10×10³	Ki	CHEMBL577123	ChEMBL ↗
26746 ↗	NS(=O)(=O)c1cc2c(cc1Cl)NC(C(Cl)Cl)NS2(=O)=O	CHEMBL205 ↗ UniProt: P00918 ↗	91.00	Ki	CHEMBL1054	ChEMBL ↗
26747 ↗	NS(=O)(=O)c1cc(C2(O)NC(=O)c3ccccc32)ccc1Cl	CHEMBL205 ↗ UniProt: P00918 ↗	138.00	Ki	CHEMBL1055	ChEMBL ↗
26748 ↗	NS(=O)(=O)c1ccc(SCCO)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	21.00	Ki	CHEMBL106848	ChEMBL ↗
26749 ↗	CCCCC(CC)C(N)=O	CHEMBL205 ↗ UniProt: P00918 ↗	3.45×10³	Ki	CHEMBL1081233	ChEMBL ↗
26750 ↗	CCC(CC)C(=O)NCCc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	33.80	Ki	CHEMBL1082898	ChEMBL ↗
26751 ↗	CCC(C)C(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	142.00	Ki	CHEMBL1083381	ChEMBL ↗
26752 ↗	CCC(C)C(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)C	CHEMBL205 ↗ UniProt: P00918 ↗	106.00	Ki	CHEMBL1083382	ChEMBL ↗
26753 ↗	CCCC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)(C)C	CHEMBL205 ↗ UniProt: P00918 ↗	10.10	Ki	CHEMBL1083383	ChEMBL ↗
26754 ↗	CCC(CC(C)C)C(=O)Nc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	104.00	Ki	CHEMBL1083684	ChEMBL ↗
26755 ↗	CCC(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	2.81×10³	Ki	CHEMBL1083756	ChEMBL ↗
26756 ↗	CCCC(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	321.00	Ki	CHEMBL1084063	ChEMBL ↗
26757 ↗	CCCC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)C	CHEMBL205 ↗ UniProt: P00918 ↗	190.00	Ki	CHEMBL1084064	ChEMBL ↗
26758 ↗	CCCC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)CC	CHEMBL205 ↗ UniProt: P00918 ↗	233.00	Ki	CHEMBL1084702	ChEMBL ↗
26759 ↗	CCC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)(C)C	CHEMBL205 ↗ UniProt: P00918 ↗	9.60	Ki	CHEMBL1084856	ChEMBL ↗
26760 ↗	CC(C)(C)C(=O)NCc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	28.60	Ki	CHEMBL1084951	ChEMBL ↗
26761 ↗	CCC(C)CC(=O)Nc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	10.30	Ki	CHEMBL1085033	ChEMBL ↗
26762 ↗	CCCCC(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	10.20	Ki	CHEMBL1085034	ChEMBL ↗
26763 ↗	NS(=O)(=O)c1ccc(NC(=O)CCCCCNc2ccn(O)c(=O)n2)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	13.00	Ki	CHEMBL1085047	ChEMBL ↗
26764 ↗	NS(=O)(=O)c1ccc(CCNC(=O)CCCCCNc2ccn(O)c(=O)n2)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	25.00	Ki	CHEMBL1085048	ChEMBL ↗
26765 ↗	CC(C)C(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)C	CHEMBL205 ↗ UniProt: P00918 ↗	237.00	Ki	CHEMBL1085092	ChEMBL ↗
26766 ↗	CC(C)C(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)(C)C	CHEMBL205 ↗ UniProt: P00918 ↗	258.00	Ki	CHEMBL1085093	ChEMBL ↗
26767 ↗	CC(C)(C)CC(=O)Nc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	3.50×10³	Ki	CHEMBL1085094	ChEMBL ↗
26768 ↗	CCCC(C)C(=O)Nc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	220.00	Ki	CHEMBL1085095	ChEMBL ↗
26769 ↗	NS(=O)(=O)c1ccc(NC(=O)CCCNc2ccn(O)c(=O)n2)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	31.00	Ki	CHEMBL1085238	ChEMBL ↗
26770 ↗	CCC(C)C(=O)Nc1ccc(S(N)(=O)=O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	339.00	Ki	CHEMBL1085467	ChEMBL ↗
26771 ↗	COC(=O)CCCCCNc1ccn(O)c(=O)n1	CHEMBL205 ↗ UniProt: P00918 ↗	270.00×10³	Ki	CHEMBL1085500	ChEMBL ↗
26772 ↗	NS(=O)(=O)c1ccc(CCNC(=O)CCCNc2ccn(O)c(=O)n2)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	28.00	Ki	CHEMBL1085555	ChEMBL ↗
26773 ↗	NS(=O)(=O)c1ccc(CNS(=O)(=O)[C@@H]2O[C@H](C(=O)O)[C@H](O)[C@H](O)[C@H]2O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	7.10	Ki	CHEMBL1088997	ChEMBL ↗
26774 ↗	NS(=O)(=O)c1ccc(CNS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	5.00	Ki	CHEMBL1088998	ChEMBL ↗
26775 ↗	CC(=O)OC[C@H]1O[C@@H](SNCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O	CHEMBL205 ↗ UniProt: P00918 ↗	14.80	Ki	CHEMBL1089015	ChEMBL ↗
26776 ↗	NS(=O)(=O)c1ccc(CNS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1	CHEMBL205 ↗ UniProt: P00918 ↗	4.80	Ki	CHEMBL1089329	ChEMBL ↗

CHEMBL205 Ki

Embeddings