CHEMBL206 IC50
BioactivityChEMBL CHEMBL206 IC50 bioactivity data
1930 compounds · Target: Estrogen receptor ( CHEMBL206 ↗ ) · UniProt: P03372 ↗ · IC50
Estrogen receptor, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
6261 ↗ |
CO[C@H]1/C=C\C=C(/C)C(=O)NC2=CC(=O)C(NCC#CCC[C@@H]3C[C@H]4[C@@H]5CCc6cc(O)ccc6[C@H]5CC[C@]4(C)[C@H]3O)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O)C2=O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
220.00 | IC50 | CHEMBL4237833 | ChEMBL ↗ |
|
6262 ↗ |
CO[C@H]1/C=C\C=C(/C)C(=O)NC2=CC(=O)C(NC/C=C/CCC[C@@H]3C[C@H]4[C@@H]5CCc6cc(O)ccc6[C@H]5CC[C@]4(C)[C@H]3O)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O)C2=O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
80.00 | IC50 | CHEMBL4246725 | ChEMBL ↗ |
|
6306 ↗ |
CO[C@H]1/C=C\C=C(/C)C(=O)NC2=CC(=O)C(NC/C=C/C[C@@H]3C[C@H]4[C@@H]5CCc6cc(O)ccc6[C@H]5CC[C@]4(C)[C@H]3O)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O)C2=O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
80.00 | IC50 | CHEMBL4475271 | ChEMBL ↗ |
|
7118 ↗ |
C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCCCCCCC(=O)NO)[C@H]3[C@@H]1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
785.00 | IC50 | CHEMBL3735106 | ChEMBL ↗ |
|
8219 ↗ |
CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)Cc2ccc(-c3cn(CCCCCC(=O)NO)nn3)cc2)cc1)c1ccccc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
248.00 | IC50 | CHEMBL2401848 | ChEMBL ↗ |
|
8220 ↗ |
CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)Cc2ccc(NC(=O)CCCCCCC(=O)NO)cc2)cc1)c1ccccc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
127.00 | IC50 | CHEMBL2401849 | ChEMBL ↗ |
|
8388 ↗ |
COC(=O)CCCCCCC(=O)Nc1ccc(OS(=O)(=O)C2CC3OC2C(c2ccc(O)cc2)=C3c2ccc(O)cc2)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
10.80×103 | IC50 | CHEMBL3589347 | ChEMBL ↗ |
|
8389 ↗ |
O=C(O)CCCCCCC(=O)Nc1ccc(OS(=O)(=O)C2CC3OC2C(c2ccc(O)cc2)=C3c2ccc(O)cc2)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
50.00 | IC50 | CHEMBL3589349 | ChEMBL ↗ |
|
8391 ↗ |
COc1ccc(OS(=O)(=O)C2CC3OC2C(c2ccc(NC(=O)CCCCCCC(=O)O)cc2)=C3c2ccc(O)cc2)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
115.60×103 | IC50 | CHEMBL3589354 | ChEMBL ↗ |
|
8392 ↗ |
Cc1ccccc1OS(=O)(=O)C1CC2OC1C(c1ccc(NC(=O)CCCCCCC(=O)O)cc1)=C2c1ccc(O)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
460.00 | IC50 | CHEMBL3589356 | ChEMBL ↗ |
|
8395 ↗ |
O=C(O)CCCCCCC(=O)Nc1ccc(C2=C(c3ccc(O)cc3)C3CC(S(=O)(=O)Oc4ccc(C(F)(F)F)cc4)C2O3)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
790.00 | IC50 | CHEMBL3589364 | ChEMBL ↗ |
|
8396 ↗ |
O=C(O)CCCCCCC(=O)Nc1ccc(C2=C(c3ccc(O)cc3)C3CC(S(=O)(=O)Oc4ccc5ccccc5c4)C2O3)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
920.00 | IC50 | CHEMBL3589368 | ChEMBL ↗ |
|
8399 ↗ |
O=C(CCCCCCC(=O)Nc1ccc(C2=C(c3ccc(O)cc3)C3CC(S(=O)(=O)Oc4ccc5ccccc5c4)C2O3)cc1)NO
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
160.00 | IC50 | CHEMBL3589701 | ChEMBL ↗ |
|
8996 ↗ |
CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccc(CCCCC(=O)NO)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
820.00 | IC50 | CHEMBL4237922 | ChEMBL ↗ |
|
8997 ↗ |
CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccc(OCCCCC(=O)NO)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
800.00 | IC50 | CHEMBL4238322 | ChEMBL ↗ |
|
8999 ↗ |
CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccc(CCC(=O)NO)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
1.94×103 | IC50 | CHEMBL4240593 | ChEMBL ↗ |
|
9006 ↗ |
CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccc(C(=O)NO)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
1.12×103 | IC50 | CHEMBL4244181 | ChEMBL ↗ |
|
9695 ↗ |
CN(c1ccccc1Cl)S(=O)(=O)C1CC2OC1C(c1ccc(NC(=O)CCCCCCC(=O)O)cc1)=C2c1ccc(O)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
5.08×103 | IC50 | CHEMBL4855392 | ChEMBL ↗ |
|
9889 ↗ |
CC(C)(F)CN1CCc2cc(O)ccc2C1c1ccc(OCCCCCC(=O)NO)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
102.40 | IC50 | CHEMBL5078131 | ChEMBL ↗ |
|
9949 ↗ |
CC(C)(F)CN1CCc2cc(O)ccc2C1c1ccc(OCCCCCCC(=O)NO)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
90.80 | IC50 | CHEMBL5090940 | ChEMBL ↗ |
|
9952 ↗ |
CC(C)(F)CN1CCc2cc(O)ccc2C1c1ccc(OC2CN(CC(=O)NO)C2)cc1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
78.20 | IC50 | CHEMBL5091589 | ChEMBL ↗ |
|
10257 ↗ |
CC#C[C@@]1(O)CC[C@@]2(CC)c3ccc(O)cc3CC[C@@H]2C1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
89.00 | IC50 | CHEMBL10560 | ChEMBL ↗ |
|
10397 ↗ |
CCC[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
5.16×103 | IC50 | CHEMBL201517 | ChEMBL ↗ |
|
10398 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C\Cl)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
6.69×103 | IC50 | CHEMBL201569 | ChEMBL ↗ |
|
10400 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C\F)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
4.28×103 | IC50 | CHEMBL202007 | ChEMBL ↗ |
|
10401 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C/F)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
4.17×103 | IC50 | CHEMBL202400 | ChEMBL ↗ |
|
10402 ↗ |
C/C=C/[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
1.16×103 | IC50 | CHEMBL202415 | ChEMBL ↗ |
|
10405 ↗ |
C#CC[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
4.64×103 | IC50 | CHEMBL203561 | ChEMBL ↗ |
|
10407 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C/Br)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
3.98×103 | IC50 | CHEMBL204317 | ChEMBL ↗ |
|
10409 ↗ |
C=C[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@]2(C)O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
1.05×103 | IC50 | CHEMBL204642 | ChEMBL ↗ |
|
10544 ↗ |
CCC(CC)(c1ccc(N)c(C)c1)c1ccc(O)c(C)c1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
98.00 | IC50 | CHEMBL2403348 | ChEMBL ↗ |
|
10545 ↗ |
CC[Si](CC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
50.85 | IC50 | CHEMBL2403349 | ChEMBL ↗ |
|
10548 ↗ |
CCCC(CCC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
4.01 | IC50 | CHEMBL2403356 | ChEMBL ↗ |
|
10549 ↗ |
COc1cc(CNC(=O)[C@@]2(Cc3ccccc3)OC(=O)N([C@@H]3CCc4ccccc43)C2=O)cc(OC)c1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
17.00×103 | IC50 | CHEMBL2407647 | ChEMBL ↗ |
|
10576 ↗ |
COC[C@]1(OC)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(/C=N/O)cc3)C[C@@]21C
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
1.90×103 | IC50 | CHEMBL267431 | ChEMBL ↗ |
|
10703 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(-c4cc[nH]n4)ccc3[nH]2)C1=O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
6.30×103 | IC50 | CHEMBL3576885 | ChEMBL ↗ |
|
10704 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(Cl)ccc3[nH]2)C1=O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
3.30×103 | IC50 | CHEMBL3578271 | ChEMBL ↗ |
|
10705 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(C(F)(F)F)ccc3[nH]2)C1=O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
3.00×103 | IC50 | CHEMBL3578274 | ChEMBL ↗ |
|
10706 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(NS(C)(=O)=O)ccc3[nH]2)C1=O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
17.00×103 | IC50 | CHEMBL3578276 | ChEMBL ↗ |
|
10707 ↗ |
Cc1nocc1-c1ccc2[nH]c([C@@]3(Cc4ccccc4)OC(=O)N([C@H](C)c4ccc(F)cc4)C3=O)nc2c1
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
4.90×103 | IC50 | CHEMBL3578284 | ChEMBL ↗ |
|
10708 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(N4CCOCC4)ccc3[nH]2)C1=O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
6.10×103 | IC50 | CHEMBL3578285 | ChEMBL ↗ |
|
10709 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(-c4cccnc4)ccc3[nH]2)C1=O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
7.90×103 | IC50 | CHEMBL3578286 | ChEMBL ↗ |
|
10727 ↗ |
C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(/C=C/C(=O)O)cc2F)N1CC(C)(C)F
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
318.24×10-3 | IC50 | CHEMBL3623004 | ChEMBL ↗ |
|
10750 ↗ |
C/C=C/C1=CC2=C(CO1)C(=O)[C@]1(C)OC(=O)[C@H](C(O)CCCCC)C1C2
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
16.00×103 | IC50 | CHEMBL3667040 | ChEMBL ↗ |
|
10790 ↗ |
C=CC[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
1.74×103 | IC50 | CHEMBL369979 | ChEMBL ↗ |
|
10791 ↗ |
CC/C=C\[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
3.04×103 | IC50 | CHEMBL369991 | ChEMBL ↗ |
|
10792 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C/Cl)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
5.60×103 | IC50 | CHEMBL370236 | ChEMBL ↗ |
|
10793 ↗ |
C=C[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
2.24×103 | IC50 | CHEMBL373019 | ChEMBL ↗ |
|
10803 ↗ |
CO/C=C\[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
3.35×103 | IC50 | CHEMBL380876 | ChEMBL ↗ |
|
10804 ↗ |
C#C[C@]1(O)CCC2C3CC=C4C[C@@H](O)CC[C@]4(C=C)C3CC[C@@]21C
|
CHEMBL206 ↗
UniProt: P03372 ↗ |
147.00 | IC50 | CHEMBL381566 | ChEMBL ↗ |