CHEMBL218 Ki
BioactivityChEMBL CHEMBL218 Ki bioactivity data
2528 compounds · Target: Cannabinoid receptor 1 ( CHEMBL218 ↗ ) · UniProt: P21554 ↗ · Ki
Cannabinoid receptor 1, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
11612 ↗ |
CN(CCCCCCCOc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(-c3ccccc3)cc2)cc1)Cc1ccccc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
3.12×103 | Ki | CHEMBL2160219 | ChEMBL ↗ |
|
11616 ↗ |
CCN(CC)CCOc1cccc(C(=O)c2c(-c3ccc(OCCCCCCCN(C)Cc4ccccc4)cc3)oc3ccccc23)c1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
2.57×103 | Ki | CHEMBL2160223 | ChEMBL ↗ |
|
11618 ↗ |
CN(CCCCCCCOc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(OCCN3CCOCC3)cc2)cc1)Cc1ccccc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
550.00 | Ki | CHEMBL2160225 | ChEMBL ↗ |
|
11818 ↗ |
c1ccc2c(COc3nn(CCN4CCCC4)c4ccccc34)cccc2c1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
560.00 | Ki | CHEMBL3116283 | ChEMBL ↗ |
|
11819 ↗ |
c1ccc2c(COc3nn(CCN4CCCCC4)c4ccccc34)cccc2c1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
3.00×103 | Ki | CHEMBL3116284 | ChEMBL ↗ |
|
11820 ↗ |
c1ccc2cc(COc3nn(CCN4CCCCC4)c4ccccc34)ccc2c1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
1.40×103 | Ki | CHEMBL3116286 | ChEMBL ↗ |
|
11821 ↗ |
O=[N+]([O-])c1ccc2c(c1)c(OCc1cccc3ccccc13)nn2CCN1CCCC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
600.00 | Ki | CHEMBL3116291 | ChEMBL ↗ |
|
11822 ↗ |
O=[N+]([O-])c1ccc2c(c1)c(OCc1ccc3ccccc3c1)nn2CCN1CCCCC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
1.30×103 | Ki | CHEMBL3116294 | ChEMBL ↗ |
|
11823 ↗ |
Nc1ccc2c(c1)c(OCc1cccc3ccccc13)nn2CCN1CCCC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
11.00×103 | Ki | CHEMBL3116299 | ChEMBL ↗ |
|
11825 ↗ |
Brc1ccc2c(c1)c(OCc1ccc3ccccc3c1)nn2CCN1CCCCC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
1.70×103 | Ki | CHEMBL3116301 | ChEMBL ↗ |
|
12552 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N4CCCCC4)ccc3n2CCC(C)C)cc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
17.00×103 | Ki | CHEMBL4104311 | ChEMBL ↗ |
|
12747 ↗ |
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(NCc3ccc(F)cc3)cc2)cc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
780.00 | Ki | CHEMBL4442990 | ChEMBL ↗ |
|
12775 ↗ |
CCCCCNc1ccc(C(=O)c2c(-c3ccc(OC)cc3)oc3ccccc23)cc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
80.00 | Ki | CHEMBL4454301 | ChEMBL ↗ |
|
12845 ↗ |
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(OCCCN(C)Cc3ccccc3)cc2)cc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
500.00 | Ki | CHEMBL4527727 | ChEMBL ↗ |
|
12864 ↗ |
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(OCCCCCN(C)Cc3ccccc3)cc2)cc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
1.76×103 | Ki | CHEMBL4539701 | ChEMBL ↗ |
|
12878 ↗ |
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(OCCCCN(C)Cc3ccccc3)cc2)cc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
860.00 | Ki | CHEMBL4552932 | ChEMBL ↗ |
|
12924 ↗ |
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(OCCN(C)Cc3ccccc3)cc2)cc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
430.00 | Ki | CHEMBL4587421 | ChEMBL ↗ |
|
13335 ↗ |
CN(CCCCCCCOc1ccc(-c2cc3ccccc3o2)cc1)Cc1ccccc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
2.80×103 | Ki | CHEMBL497755 | ChEMBL ↗ |
|
13395 ↗ |
CN(CCCCCCCOc1ccc(-c2oc3ccccc3c2C(=O)c2ccccc2)cc1)Cc1ccccc1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
320.00 | Ki | CHEMBL511575 | ChEMBL ↗ |
|
43613 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)C1=NN(c2ccc(Cl)cc2)[C@H](c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
280.00 | Ki | CHEMBL1076584 | ChEMBL ↗ |
|
43614 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
7.50 | Ki | CHEMBL1076636 | ChEMBL ↗ |
|
43615 ↗ |
O=C(C1CCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
291.00 | Ki | CHEMBL1076884 | ChEMBL ↗ |
|
43616 ↗ |
CN/C(=N\S(=O)(=O)c1ccc(F)cc1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
21.70 | Ki | CHEMBL1079628 | ChEMBL ↗ |
|
43617 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)C1=NN(c2ccc(Cl)cc2)[C@@H](c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
2.00 | Ki | CHEMBL1080156 | ChEMBL ↗ |
|
43618 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)C1=NN(c2ccc(Cl)cc2)[C@H](c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
58.00 | Ki | CHEMBL1080157 | ChEMBL ↗ |
|
43619 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
4.70 | Ki | CHEMBL1080545 | ChEMBL ↗ |
|
43620 ↗ |
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)OCCO1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
500.00×10-3 | Ki | CHEMBL108085 | ChEMBL ↗ |
|
43621 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1C[C@@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
140.00 | Ki | CHEMBL1080908 | ChEMBL ↗ |
|
43622 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
42.00 | Ki | CHEMBL1080916 | ChEMBL ↗ |
|
43623 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)N1C[C@@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
463.00 | Ki | CHEMBL1080917 | ChEMBL ↗ |
|
43624 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
14.50 | Ki | CHEMBL1081213 | ChEMBL ↗ |
|
43625 ↗ |
CN/C(=N\S(=O)(=O)N1CCCCC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
58.00 | Ki | CHEMBL1081285 | ChEMBL ↗ |
|
43626 ↗ |
CN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
84.00 | Ki | CHEMBL1081286 | ChEMBL ↗ |
|
43627 ↗ |
CN/C(=N\S(=O)(=O)c1cccc(Cl)c1)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
53.00 | Ki | CHEMBL1081304 | ChEMBL ↗ |
|
43628 ↗ |
CN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
37.00 | Ki | CHEMBL1081305 | ChEMBL ↗ |
|
43629 ↗ |
CN/C(=N\S(=O)(=O)c1ccc(C(F)(F)F)cc1)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
11.30 | Ki | CHEMBL1081306 | ChEMBL ↗ |
|
43630 ↗ |
CN/C(=N\S(=O)(=O)N1CCCCC1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
141.00 | Ki | CHEMBL1081650 | ChEMBL ↗ |
|
43631 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(F)CC1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
55.00 | Ki | CHEMBL1081832 | ChEMBL ↗ |
|
43632 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
7.60 | Ki | CHEMBL1081992 | ChEMBL ↗ |
|
43633 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
38.80 | Ki | CHEMBL1081993 | ChEMBL ↗ |
|
43634 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)C1=NN(c2ccc(Cl)cc2)[C@@H](c2ccccc2)C1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
9.20 | Ki | CHEMBL1082018 | ChEMBL ↗ |
|
43635 ↗ |
O=C(NC1CCCCC1)N1CCN(C(c2ccc(C(F)(F)F)cc2)c2ccc(Cl)cc2Cl)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
1.20 | Ki | CHEMBL1084429 | ChEMBL ↗ |
|
43636 ↗ |
O=C(NC1CCCCC1)N1CCN(C(c2ccc(F)cc2)c2ccc(Cl)cc2Cl)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
2.50 | Ki | CHEMBL1084695 | ChEMBL ↗ |
|
43637 ↗ |
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(F)cc2Cl)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
8.10 | Ki | CHEMBL1086605 | ChEMBL ↗ |
|
43638 ↗ |
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2ccccc2)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
52.00 | Ki | CHEMBL1086903 | ChEMBL ↗ |
|
43639 ↗ |
CCCCNC(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
239.00 | Ki | CHEMBL1087032 | ChEMBL ↗ |
|
43640 ↗ |
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2c(Cl)cccc2Cl)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
2.20 | Ki | CHEMBL1087250 | ChEMBL ↗ |
|
43641 ↗ |
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Br)cc2F)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
1.80 | Ki | CHEMBL1087251 | ChEMBL ↗ |
|
43642 ↗ |
O=C(C1CCCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
732.00 | Ki | CHEMBL1087521 | ChEMBL ↗ |
|
43643 ↗ |
O=C(C1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1
|
CHEMBL218 ↗
UniProt: P21554 ↗ |
5.80 | Ki | CHEMBL1087644 | ChEMBL ↗ |