CHEMBL222 Ki
BioactivityChEMBL CHEMBL222 Ki bioactivity data
1058 compounds · Target: Sodium-dependent noradrenaline transporter ( CHEMBL222 ↗ ) · UniProt: P23975 ↗ · Ki
Sodium-dependent noradrenaline transporter, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
33785 ↗ |
CCCCN1CCC(COC(=O)c2cc(Cl)c(NC)c3c2OCCO3)CC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
3.23×103 | Ki | CHEMBL1258223 | ChEMBL ↗ |
|
33889 ↗ |
c1ccc(Oc2ccccc2OC2CNC2)cc1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.64×103 | Ki | CHEMBL1645596 | ChEMBL ↗ |
|
33890 ↗ |
Fc1ccccc1Oc1ccccc1OC1CNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
528.00 | Ki | CHEMBL1645597 | ChEMBL ↗ |
|
33891 ↗ |
Fc1ccccc1Oc1cccc(F)c1OC1CNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
507.00 | Ki | CHEMBL1645598 | ChEMBL ↗ |
|
33892 ↗ |
Fc1cccc(Oc2ccccc2Cl)c1OC1CNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
198.00 | Ki | CHEMBL1645599 | ChEMBL ↗ |
|
33893 ↗ |
Fc1cccc(Cl)c1Oc1cccc(F)c1OC1CNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
138.00 | Ki | CHEMBL1645600 | ChEMBL ↗ |
|
33894 ↗ |
Cc1cccc(F)c1Oc1cccc(F)c1OC1CNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
116.00 | Ki | CHEMBL1645601 | ChEMBL ↗ |
|
33895 ↗ |
Fc1cccc(Oc2c(Cl)cccc2Cl)c1OC1CNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
164.00 | Ki | CHEMBL1645603 | ChEMBL ↗ |
|
33896 ↗ |
Cc1cccc(Cl)c1Oc1cccc(F)c1OC1CNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
433.00 | Ki | CHEMBL1645604 | ChEMBL ↗ |
|
33897 ↗ |
Fc1cccc(Oc2cccc(Cl)c2Cl)c1OC1CNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
374.00 | Ki | CHEMBL1645605 | ChEMBL ↗ |
|
33898 ↗ |
Fc1ccccc1Oc1ccccc1OC1CCNCC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.00×103 | Ki | CHEMBL1645606 | ChEMBL ↗ |
|
33899 ↗ |
Fc1ccccc1Oc1cccc(F)c1OC1CCNCC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
489.00 | Ki | CHEMBL1645607 | ChEMBL ↗ |
|
33900 ↗ |
Fc1cccc(Cl)c1Oc1cccc(F)c1OC1CCNCC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
218.00 | Ki | CHEMBL1645608 | ChEMBL ↗ |
|
33901 ↗ |
Cc1cccc(F)c1Oc1cccc(F)c1OC1CCNCC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
323.00 | Ki | CHEMBL1645609 | ChEMBL ↗ |
|
33902 ↗ |
Fc1ccccc1Oc1cccc(F)c1OC1CCCNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.95×103 | Ki | CHEMBL1645610 | ChEMBL ↗ |
|
33903 ↗ |
Fc1ccccc1Oc1ccccc1OC1CCNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.35×103 | Ki | CHEMBL1645611 | ChEMBL ↗ |
|
33904 ↗ |
Fc1ccccc1Oc1cccc(F)c1OC1CCNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.02×103 | Ki | CHEMBL1645612 | ChEMBL ↗ |
|
33905 ↗ |
Fc1cccc(Oc2ccccc2Cl)c1OC1CCNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
192.00 | Ki | CHEMBL1645613 | ChEMBL ↗ |
|
33906 ↗ |
Cc1cccc(F)c1Oc1cccc(F)c1OC1CCNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
328.00 | Ki | CHEMBL1645614 | ChEMBL ↗ |
|
33907 ↗ |
Fc1cccc(Cl)c1Oc1cccc(F)c1OC1CCNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
226.00 | Ki | CHEMBL1645615 | ChEMBL ↗ |
|
33908 ↗ |
Fc1cccc(Cl)c1Oc1cccc(F)c1O[C@H]1CCNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.01×103 | Ki | CHEMBL1645616 | ChEMBL ↗ |
|
33909 ↗ |
Fc1cccc(Cl)c1Oc1cccc(F)c1O[C@@H]1CCNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
110.00 | Ki | CHEMBL1645617 | ChEMBL ↗ |
|
33910 ↗ |
Fc1cccc(Cl)c1Oc1ncccc1OC1CCNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.14×103 | Ki | CHEMBL1645618 | ChEMBL ↗ |
|
33911 ↗ |
Fc1cccc(Cl)c1Oc1ncccc1OC1CNC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
73.00 | Ki | CHEMBL1645619 | ChEMBL ↗ |
|
33991 ↗ |
COc1cc2c(cc1OC)CN(CCCCn1cc(-c3ccc(F)cc3)c3ccccc31)CC2
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.35×103 | Ki | CHEMBL1831166 | ChEMBL ↗ |
|
34032 ↗ |
OC1(c2ccc(Cl)cc2)CCN(CCCCc2ccc(F)cc2)CC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.23×103 | Ki | CHEMBL1940402 | ChEMBL ↗ |
|
34090 ↗ |
Cn1c(=O)cnn(CCCCN2CCN(c3cccc4ccc(O[11CH3])cc34)CC2)c1=O
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
6.98×103 | Ki | CHEMBL199824 | ChEMBL ↗ |
|
34147 ↗ |
O=C(CCCCN1CCC(c2ccccc2)CC1)c1nc2ccccc2s1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
49.00 | Ki | CHEMBL2037531 | ChEMBL ↗ |
|
34503 ↗ |
CC(N)Cc1c[nH]c2ccccc12
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
642.00 | Ki | CHEMBL30713 | ChEMBL ↗ |
|
34509 ↗ |
CN1CCc2c(c3cccc4c3n2Cc2ccccc2C4)C1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.35×103 | Ki | CHEMBL3104092 | ChEMBL ↗ |
|
34610 ↗ |
c1cnc(N2CCN(CCCc3nc4ccccc4s3)CC2)nc1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
2.76×103 | Ki | CHEMBL3289656 | ChEMBL ↗ |
|
34621 ↗ |
OC1(c2ccc(Cl)cc2)CC2CCC(C1)N2CCCOc1ccc(F)cc1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.79×103 | Ki | CHEMBL3321789 | ChEMBL ↗ |
|
34622 ↗ |
OC1(c2ccc(Cl)cc2)CC2CCC(C1)N2CCCSc1ccc(F)cc1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.41×103 | Ki | CHEMBL3321790 | ChEMBL ↗ |
|
34623 ↗ |
OC1(c2ccc(Cl)cc2)CC2CCC(C1)N2CCCSc1cccc(F)c1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
510.00 | Ki | CHEMBL3321791 | ChEMBL ↗ |
|
34624 ↗ |
OC1(c2ccc(Cl)cc2)CC2CCC(C1)N2CCCSc1ccccc1F
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
462.00 | Ki | CHEMBL3321792 | ChEMBL ↗ |
|
34923 ↗ |
COc1ccc(CCN(CCCc2ccccc2)CCc2ccc3c(c2)OCO3)cc1OC
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
11.00 | Ki | CHEMBL3735756 | ChEMBL ↗ |
|
34962 ↗ |
C=CCN(CC=C)CCc1c[nH]c2ccccc12
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.00×103 | Ki | CHEMBL3752576 | ChEMBL ↗ |
|
34963 ↗ |
C=CCN(CC=C)CCc1c[nH]c2ccc(Cl)cc12
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
630.96 | Ki | CHEMBL3752900 | ChEMBL ↗ |
|
34965 ↗ |
C=CCN(CC=C)CCc1c[nH]c2ccc(Br)cc12
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.00×103 | Ki | CHEMBL3754166 | ChEMBL ↗ |
|
34966 ↗ |
C=CCN(CC=C)CCc1c[nH]c2ccc(F)cc12
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
2.00×103 | Ki | CHEMBL3754496 | ChEMBL ↗ |
|
35278 ↗ |
COc1ccccc1N1CCC2(CCN(CCCSc3nnc(-c4ccccc4)n3C)CC2)CC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
931.00 | Ki | CHEMBL4084262 | ChEMBL ↗ |
|
35340 ↗ |
COc1cccc(-c2ccc3c(c2)CN(Cc2ccccc2)C3)c1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
100.00 | Ki | CHEMBL4167315 | ChEMBL ↗ |
|
35342 ↗ |
CCOC(=O)CCN1CCN(c2ccc3c(c2)CN(C(=O)OCc2ccccc2)CC3)CC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.06×103 | Ki | CHEMBL4169689 | ChEMBL ↗ |
|
35430 ↗ |
NCCCCCCn1cc(CCCCN2CCC(c3ccc(-c4cc(C(=O)O)cc5cc(-c6ccc(C(F)(F)F)cc6)ccc45)cc3)CC2)nn1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.87×103 | Ki | CHEMBL4216870 | ChEMBL ↗ |
|
35771 ↗ |
CC[C@H]1c2cc(OC)ccc2CC[C@@]1(C)N
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
2.51×103 | Ki | CHEMBL4472703 | ChEMBL ↗ |
|
35817 ↗ |
CNCc1ccccc1-c1csc([C@H](C)Nc2nc(C)nc3cc(OC)c(OC)cc23)c1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
2.08×103 | Ki | CHEMBL4520788 | ChEMBL ↗ |
|
35830 ↗ |
CC[C@H]1c2cc(C)ccc2OC[C@@]1(C)N
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
316.23 | Ki | CHEMBL4528651 | ChEMBL ↗ |
|
35914 ↗ |
CC[C@H]1c2ccccc2N(c2ccccc2)C[C@@]1(C)N
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
398.11 | Ki | CHEMBL4572167 | ChEMBL ↗ |
|
36144 ↗ |
CC(C)(C)OC(=O)N1CCCC1CN[C@H]1CC[C@@](c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
2.43×103 | Ki | CHEMBL4777443 | ChEMBL ↗ |
|
36313 ↗ |
O=S(=O)(c1cccc(F)c1)n1ccc2c(N3CCNCC3)nc3ccccc3c21
|
CHEMBL222 ↗
UniProt: P23975 ↗ |
1.24×103 | Ki | CHEMBL4867565 | ChEMBL ↗ |