CHEMBL2326 Ki
BioactivityChEMBL CHEMBL2326 Ki bioactivity data
1002 compounds · Target: Carbonic anhydrase 7 ( CHEMBL2326 ↗ ) · UniProt: P43166 ↗ · Ki
Carbonic anhydrase 7, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
5372 ↗ |
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
8.14×103 | Ki | CHEMBL1336 | ChEMBL ↗ |
|
6570 ↗ |
O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
7.55×103 | Ki | CHEMBL6246 | ChEMBL ↗ |
|
6574 ↗ |
Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1Nc1nccc(-c2cccnc2)n1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
109.00 | Ki | CHEMBL941 | ChEMBL ↗ |
|
6753 ↗ |
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
6.94×103 | Ki | CHEMBL325041 | ChEMBL ↗ |
|
8041 ↗ |
Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
2.17×103 | Ki | CHEMBL118 | ChEMBL ↗ |
|
10445 ↗ |
CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
3.50 | Ki | CHEMBL218490 | ChEMBL ↗ |
|
11601 ↗ |
Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
70.00 | Ki | CHEMBL21 | ChEMBL ↗ |
|
11815 ↗ |
O=C1NS(=O)(=O)c2ccccc21
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
10.00 | Ki | CHEMBL310671 | ChEMBL ↗ |
|
13340 ↗ |
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
4.84×103 | Ki | CHEMBL50 | ChEMBL ↗ |
|
14315 ↗ |
Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
4.35×103 | Ki | CHEMBL165 | ChEMBL ↗ |
|
14767 ↗ |
O=c1c(O)c(-c2ccccc2)oc2cc(O)cc(O)c12
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
24.50 | Ki | CHEMBL309490 | ChEMBL ↗ |
|
16141 ↗ |
O=C1C[C@@H](c2ccc(O)cc2)Oc2cc(O)cc(O)c21
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
4.30 | Ki | CHEMBL9352 | ChEMBL ↗ |
|
17675 ↗ |
O=c1c(O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
25.00 | Ki | CHEMBL150 | ChEMBL ↗ |
|
17678 ↗ |
O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
4.70 | Ki | CHEMBL151 | ChEMBL ↗ |
|
17957 ↗ |
Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
99.00 | Ki | CHEMBL255863 | ChEMBL ↗ |
|
19961 ↗ |
NS(=O)(=O)Oc1ccc2c3c(c(=O)oc2c1)CCCCC3
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
23.00 | Ki | CHEMBL286738 | ChEMBL ↗ |
|
20840 ↗ |
COc1cc(/C=C/C(=O)/C=C(O)/C=C/c2ccc(O)c(OC)c2)ccc1O
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
9.30×103 | Ki | CHEMBL116438 | ChEMBL ↗ |
|
20908 ↗ |
O=C(O)/C=C/c1ccc(O)c(O)c1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
6.42×103 | Ki | CHEMBL145 | ChEMBL ↗ |
|
24164 ↗ |
O=c1ccc2ccc(OCc3ccccc3)cc2o1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
15.30×103 | Ki | CHEMBL145781 | ChEMBL ↗ |
|
25674 ↗ |
CCOC(=O)c1cc2ccc(OC)cc2oc1=O
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
9.70×103 | Ki | CHEMBL568385 | ChEMBL ↗ |
|
25679 ↗ |
Cc1ccc2oc(=O)c(C(=O)O)cc2c1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
32.00 | Ki | CHEMBL577123 | ChEMBL ↗ |
|
25717 ↗ |
O=C(O)c1cc2ccccc2oc1=O
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
6.20×103 | Ki | CHEMBL83294 | ChEMBL ↗ |
|
26746 ↗ |
NS(=O)(=O)c1cc2c(cc1Cl)NC(C(Cl)Cl)NS2(=O)=O
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
7.90 | Ki | CHEMBL1054 | ChEMBL ↗ |
|
26747 ↗ |
NS(=O)(=O)c1cc(C2(O)NC(=O)c3ccccc32)ccc1Cl
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
2.80 | Ki | CHEMBL1055 | ChEMBL ↗ |
|
26750 ↗ |
CCC(CC)C(=O)NCCc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
51.00 | Ki | CHEMBL1082898 | ChEMBL ↗ |
|
26751 ↗ |
CCC(C)C(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
54.00 | Ki | CHEMBL1083381 | ChEMBL ↗ |
|
26752 ↗ |
CCC(C)C(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)C
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
53.00 | Ki | CHEMBL1083382 | ChEMBL ↗ |
|
26753 ↗ |
CCCC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)(C)C
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
6.50 | Ki | CHEMBL1083383 | ChEMBL ↗ |
|
26754 ↗ |
CCC(CC(C)C)C(=O)Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
64.00 | Ki | CHEMBL1083684 | ChEMBL ↗ |
|
26755 ↗ |
CCC(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
861.00 | Ki | CHEMBL1083756 | ChEMBL ↗ |
|
26756 ↗ |
CCCC(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
60.00 | Ki | CHEMBL1084063 | ChEMBL ↗ |
|
26757 ↗ |
CCCC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)C
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
581.00 | Ki | CHEMBL1084064 | ChEMBL ↗ |
|
26758 ↗ |
CCCC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)CC
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
5.15×103 | Ki | CHEMBL1084702 | ChEMBL ↗ |
|
26759 ↗ |
CCC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)(C)C
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
49.00 | Ki | CHEMBL1084856 | ChEMBL ↗ |
|
26760 ↗ |
CC(C)(C)C(=O)NCc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
5.80 | Ki | CHEMBL1084951 | ChEMBL ↗ |
|
26761 ↗ |
CCC(C)CC(=O)Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
54.00 | Ki | CHEMBL1085033 | ChEMBL ↗ |
|
26762 ↗ |
CCCCC(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
5.00 | Ki | CHEMBL1085034 | ChEMBL ↗ |
|
26765 ↗ |
CC(C)C(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)C
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
8.37×103 | Ki | CHEMBL1085092 | ChEMBL ↗ |
|
26766 ↗ |
CC(C)C(C(=O)Nc1ccc(S(N)(=O)=O)cc1)C(C)(C)C
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
556.00 | Ki | CHEMBL1085093 | ChEMBL ↗ |
|
26767 ↗ |
CC(C)(C)CC(=O)Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
62.00 | Ki | CHEMBL1085094 | ChEMBL ↗ |
|
26768 ↗ |
CCCC(C)C(=O)Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
605.00 | Ki | CHEMBL1085095 | ChEMBL ↗ |
|
26770 ↗ |
CCC(C)C(=O)Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
65.00 | Ki | CHEMBL1085467 | ChEMBL ↗ |
|
26819 ↗ |
CC(=O)Nc1ccc(O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
9.10×103 | Ki | CHEMBL112 | ChEMBL ↗ |
|
26820 ↗ |
Nc1ccc(O)cc1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
1.36×106 | Ki | CHEMBL1142 | ChEMBL ↗ |
|
26854 ↗ |
O=c1cc(-c2ccccc2)oc2cc(O)cc(O)c12
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
171.41 | Ki | CHEMBL117 | ChEMBL ↗ |
|
26855 ↗ |
COc1ccc(C(=O)O)cc1OC
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
7.15×103 | Ki | CHEMBL118903 | ChEMBL ↗ |
|
26860 ↗ |
NS(=O)(=O)c1nnc(NC(=O)C23CC4CC(CC(C4)C2)C3)s1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
35.00 | Ki | CHEMBL1209038 | ChEMBL ↗ |
|
26861 ↗ |
NS(=O)(=O)c1nnc(NC(=O)CC23CC4CC(CC(C4)C2)C3)s1
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
48.00 | Ki | CHEMBL1209039 | ChEMBL ↗ |
|
26862 ↗ |
CC(C)(C)OC(=O)N(CCCCN(CCCNC(=O)C(F)(F)F)C(=O)OC(C)(C)C)CCCNC(=O)C(F)(F)F
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
107.00×103 | Ki | CHEMBL1212954 | ChEMBL ↗ |
|
26863 ↗ |
NCCNCCCNCCN
|
CHEMBL2326 ↗
UniProt: P43166 ↗ |
58.00×103 | Ki | CHEMBL1214193 | ChEMBL ↗ |