CHEMBL234 Ki
BioactivityChEMBL CHEMBL234 Ki bioactivity data
3050 compounds · Target: D(3) dopamine receptor ( CHEMBL234 ↗ ) · UniProt: P35462 ↗ · Ki
D(3) dopamine receptor, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
33677 ↗ |
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3c(c2)Cc2ccccc2-3)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
410.00×10-3 | Ki | CHEMBL110365 | ChEMBL ↗ |
|
33680 ↗ |
O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
3.67 | Ki | CHEMBL1112 | ChEMBL ↗ |
|
33821 ↗ |
O=C1c2ccccc2C(=O)N1CCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
794.30×10-3 | Ki | CHEMBL131495 | ChEMBL ↗ |
|
33832 ↗ |
O=C(CCCN1CCN(c2ncccn2)CC1)c1ccc(F)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
244.10 | Ki | CHEMBL140872 | ChEMBL ↗ |
|
33835 ↗ |
COc1c(O)ccc2c1CN1CCc3cc4c(cc3[C@@H]1C2)OCO4
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
82.40 | Ki | CHEMBL1457510 | ChEMBL ↗ |
|
33836 ↗ |
c1ccc2c(c1)CC(CN1CCN(c3ccc4c(c3)OCCO4)CC1)C2
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
2.84×103 | Ki | CHEMBL146556 | ChEMBL ↗ |
|
33854 ↗ |
COC(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
100.00 | Ki | CHEMBL1631532 | ChEMBL ↗ |
|
33857 ↗ |
Cc1ccc2c(N3CCN(CCc4cccc(NS(C)(=O)=O)c4)CC3)cccc2n1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
199.53 | Ki | CHEMBL1631535 | ChEMBL ↗ |
|
33862 ↗ |
Cc1ccc2c(N3CCN(CCc4cccc(N5CCNC5=O)c4)CC3)cccc2n1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
199.53 | Ki | CHEMBL1631540 | ChEMBL ↗ |
|
33864 ↗ |
Cc1ccc2c(N3CCN(CCc4cccc(N5CCOC5=O)c4)CC3)cccc2n1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
199.53 | Ki | CHEMBL1631542 | ChEMBL ↗ |
|
33867 ↗ |
Cc1ccc2c(N3CCN(CCc4cccc(-n5cccn5)c4)CC3)cccc2n1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
50.12 | Ki | CHEMBL1631545 | ChEMBL ↗ |
|
33869 ↗ |
CC(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
158.49 | Ki | CHEMBL1632206 | ChEMBL ↗ |
|
33873 ↗ |
Cc1ccc2c(N3CCN(CCc4cccc(NC(=O)c5ccccc5)c4)CC3)cccc2n1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
100.00 | Ki | CHEMBL1632210 | ChEMBL ↗ |
|
33880 ↗ |
Cc1ccc2c(N3CCN(CCc4cccc(NC(=O)c5cnccn5)c4)CC3)cccc2n1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
79.43 | Ki | CHEMBL1632217 | ChEMBL ↗ |
|
33883 ↗ |
CCNC(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
125.89 | Ki | CHEMBL1632220 | ChEMBL ↗ |
|
33886 ↗ |
Cc1ccc2c(N3CCN(CCc4cccc(NC(=O)Nc5ccccc5)c4)CC3)cccc2n1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
31.62 | Ki | CHEMBL1632223 | ChEMBL ↗ |
|
33887 ↗ |
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
209.00 | Ki | CHEMBL1644978 | ChEMBL ↗ |
|
33888 ↗ |
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
62.00 | Ki | CHEMBL1644980 | ChEMBL ↗ |
|
33912 ↗ |
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(N(C)C)cc2)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
800.00×10-3 | Ki | CHEMBL1688990 | ChEMBL ↗ |
|
33913 ↗ |
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(CCF)cc2)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
2.40 | Ki | CHEMBL1688991 | ChEMBL ↗ |
|
33978 ↗ |
O=S(=O)(c1ccccc1F)n1cc(C2=CCNCC2)c2ccccc21
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
741.00 | Ki | CHEMBL180606 | ChEMBL ↗ |
|
33991 ↗ |
COc1cc2c(cc1OC)CN(CCCCn1cc(-c3ccc(F)cc3)c3ccccc31)CC2
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
544.00 | Ki | CHEMBL1831166 | ChEMBL ↗ |
|
34032 ↗ |
OC1(c2ccc(Cl)cc2)CCN(CCCCc2ccc(F)cc2)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
667.00 | Ki | CHEMBL1940402 | ChEMBL ↗ |
|
34033 ↗ |
Fc1ccc(SCCCN2CCC(c3ccc(Cl)cc3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
130.00 | Ki | CHEMBL1940405 | ChEMBL ↗ |
|
34034 ↗ |
Fc1ccc(OCCCN2CCC(c3ccc(Cl)cc3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
696.00 | Ki | CHEMBL1940406 | ChEMBL ↗ |
|
34035 ↗ |
[O-][S+](CCCN1CCC(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
243.00 | Ki | CHEMBL1940407 | ChEMBL ↗ |
|
34036 ↗ |
Fc1ccc(CCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
261.00 | Ki | CHEMBL1940408 | ChEMBL ↗ |
|
34037 ↗ |
Fc1ccc(SCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
422.00 | Ki | CHEMBL1940409 | ChEMBL ↗ |
|
34038 ↗ |
Fc1ccc(SCCCN2CCN(c3ccc(C(F)(F)F)cc3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
544.00 | Ki | CHEMBL1940410 | ChEMBL ↗ |
|
34039 ↗ |
Fc1ccc(OCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
885.00 | Ki | CHEMBL1940411 | ChEMBL ↗ |
|
34040 ↗ |
Fc1ccc(OCCCN2CCN(c3ccccc3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
207.00 | Ki | CHEMBL1940412 | ChEMBL ↗ |
|
34041 ↗ |
Clc1ccc(N2CCN(CCCOc3ccccc3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
760.16 | Ki | CHEMBL1940413 | ChEMBL ↗ |
|
34042 ↗ |
c1ccc(OCCCN2CCN(c3ccccc3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
79.30 | Ki | CHEMBL1940414 | ChEMBL ↗ |
|
34043 ↗ |
Fc1ccc(CCCCN2CCN(c3ncccn3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
262.00 | Ki | CHEMBL1940415 | ChEMBL ↗ |
|
34044 ↗ |
Fc1ccc(SCCCN2CCN(c3ncccn3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
68.00 | Ki | CHEMBL1940416 | ChEMBL ↗ |
|
34045 ↗ |
Fc1ccc(OCCCN2CCN(c3ncccn3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
778.00 | Ki | CHEMBL1940417 | ChEMBL ↗ |
|
34046 ↗ |
Fc1ccc(CCCCN2CCN(c3ccccn3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
86.00 | Ki | CHEMBL1940418 | ChEMBL ↗ |
|
34047 ↗ |
Fc1ccc(SCCCN2CCN(c3ccccn3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
160.00 | Ki | CHEMBL1940419 | ChEMBL ↗ |
|
34048 ↗ |
Fc1ccc(OCCCN2CCN(c3ccccn3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
229.00 | Ki | CHEMBL1940420 | ChEMBL ↗ |
|
34050 ↗ |
O=C1c2ccc(F)cc2CC1CCN1CCCN(c2ccc(Cl)cc2)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
589.42 | Ki | CHEMBL1946124 | ChEMBL ↗ |
|
34051 ↗ |
Clc1ccc(N2CCCN(CCCCc3nc4ccccc4s3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
152.00 | Ki | CHEMBL1946254 | ChEMBL ↗ |
|
34052 ↗ |
Clc1ccc(N2CCCN(CCCc3nc4ccccc4s3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
863.00 | Ki | CHEMBL1946255 | ChEMBL ↗ |
|
34053 ↗ |
O=C(CCCCN1CCCN(c2ccc(Cl)cc2)CC1)c1nc2ccccc2s1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
1.05×103 | Ki | CHEMBL1946257 | ChEMBL ↗ |
|
34070 ↗ |
C[C@H]1Oc2c(cccc2N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)NC1=O
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
501.20×10-3 | Ki | CHEMBL196514 | ChEMBL ↗ |
|
34090 ↗ |
Cn1c(=O)cnn(CCCCN2CCN(c3cccc4ccc(O[11CH3])cc34)CC2)c1=O
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
62.80 | Ki | CHEMBL199824 | ChEMBL ↗ |
|
34105 ↗ |
CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
90.50×10-3 | Ki | CHEMBL2028019 | ChEMBL ↗ |
|
34132 ↗ |
Clc1ccc(N2CCN(CCCc3nc4ccccc4s3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
214.00 | Ki | CHEMBL2037430 | ChEMBL ↗ |
|
34133 ↗ |
Clc1ccc(N2CCN(CCCCc3nc4ccccc4s3)CC2)cc1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
31.00 | Ki | CHEMBL2037431 | ChEMBL ↗ |
|
34134 ↗ |
OC1(c2ccc(Cl)cc2)CCN(CCCCc2nc3ccccc3s2)CC1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
289.70 | Ki | CHEMBL2037432 | ChEMBL ↗ |
|
34137 ↗ |
O=C(CCCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1)c1nc2ccccc2s1
|
CHEMBL234 ↗
UniProt: P35462 ↗ |
63.55 | Ki | CHEMBL2037520 | ChEMBL ↗ |