CHEMBL236 Ki
BioactivityChEMBL CHEMBL236 Ki bioactivity data
2072 compounds · Target: Delta-type opioid receptor ( CHEMBL236 ↗ ) · UniProt: P41143 ↗ · Ki
Delta-type opioid receptor, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
19376 ↗ |
COc1ccc(-c2cc(=O)c3c(O)c(OC)c(O)cc3o2)cc1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
8.40×103 | Ki | CHEMBL78010 | ChEMBL ↗ |
|
33887 ↗ |
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
1.41×103 | Ki | CHEMBL1644978 | ChEMBL ↗ |
|
33888 ↗ |
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
1.53×103 | Ki | CHEMBL1644980 | ChEMBL ↗ |
|
35533 ↗ |
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCCN(c2ccc(F)cc2)c2ccc(F)cc2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
10.00×103 | Ki | CHEMBL4278465 | ChEMBL ↗ |
|
35579 ↗ |
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCN(c2ccc(F)cc2)c2ccc(F)cc2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
1.56×103 | Ki | CHEMBL4291048 | ChEMBL ↗ |
|
35591 ↗ |
COc1ccc(N(CCCCN2CCC(O)(c3ccc(Cl)c(C(F)(F)F)c3)CC2)c2ccc(OC)cc2)cc1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
10.00×103 | Ki | CHEMBL4293307 | ChEMBL ↗ |
|
35654 ↗ |
COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
10.00×103 | Ki | CHEMBL4442460 | ChEMBL ↗ |
|
35853 ↗ |
COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(F)cc2)c2ccccc2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
19.00×103 | Ki | CHEMBL4544086 | ChEMBL ↗ |
|
36069 ↗ |
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
1.71×103 | Ki | CHEMBL47050 | ChEMBL ↗ |
|
40135 ↗ |
CCCN(CCc1ccccc1)CCc1cccc(O)c1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
3.71×103 | Ki | CHEMBL1188090 | ChEMBL ↗ |
|
40782 ↗ |
CCCCCN(CCc1ccccc1)CCc1cccc(O)c1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
1.31×103 | Ki | CHEMBL2180637 | ChEMBL ↗ |
|
40785 ↗ |
CCCCN(CCc1ccccc1)CCc1cccc(O)c1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
2.43×103 | Ki | CHEMBL2180640 | ChEMBL ↗ |
|
40786 ↗ |
CCCCCCN(CCc1ccccc1)CCc1cccc(O)c1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
3.57×103 | Ki | CHEMBL2180641 | ChEMBL ↗ |
|
43532 ↗ |
CCC(=O)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
570.00 | Ki | CHEMBL596 | ChEMBL ↗ |
|
43914 ↗ |
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1O
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
6.40×103 | Ki | CHEMBL190461 | ChEMBL ↗ |
|
49346 ↗ |
COc1cccc(C2(O)CCCCC2CN(C)C)c1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
9.40 | Ki | CHEMBL1237044 | ChEMBL ↗ |
|
51292 ↗ |
CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)[C@H]2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2cc(C)c(O)c(C)c2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
3.60 | Ki | CHEMBL5077561 | ChEMBL ↗ |
|
51293 ↗ |
CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
1.10 | Ki | CHEMBL5081245 | ChEMBL ↗ |
|
51295 ↗ |
CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccc(F)cc2)NC(=O)CNC(=O)[C@H]2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2cc(C)c(O)c(C)c2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
320.00×10-3 | Ki | CHEMBL5089012 | ChEMBL ↗ |
|
51296 ↗ |
CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccc(F)cc2)NC(=O)[C@H]2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2cc(C)c(O)c(C)c2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
1.20 | Ki | CHEMBL5090705 | ChEMBL ↗ |
|
51297 ↗ |
CCCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(N(C(=O)CC)c2ccc(Cl)c(Cl)c2)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
570.00×10-3 | Ki | CHEMBL5091642 | ChEMBL ↗ |
|
52073 ↗ |
O=C1CCc2cc(Nc3cc(OC4CCOCC4)c([N+](=O)[O-])cc3Cl)ccc2N1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
1.42×103 | Ki | CHEMBL4075278 | ChEMBL ↗ |
|
53694 ↗ |
Cc1cc(NC(=O)c2cccc(S(F)(F)(F)(F)F)c2)cc(-n2ccn3nc(-c4cccnc4)cc23)c1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
1.73×103 | Ki | CHEMBL4526351 | ChEMBL ↗ |
|
57518 ↗ |
CN(C)C[C@H]1CCCC[C@]1(O)c1cccc(O)c1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
2.90×103 | Ki | CHEMBL1400 | ChEMBL ↗ |
|
58459 ↗ |
CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)CC1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
740.00×10-3 | Ki | CHEMBL5078669 | ChEMBL ↗ |
|
60739 ↗ |
COc1ccc2c(c1O)[C@]13CCN(C)C(C2)[C@@]12CC(=C(C)C)[C@@H]3c1[nH]c3ccccc3c1C2
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
103.00 | Ki | CHEMBL107207 | ChEMBL ↗ |
|
60741 ↗ |
COc1ccc2c(c1O)[C@]13CCN(C)C(C2)[C@@]12C/C(=C(/C)c1ccccc1)[C@@H]3c1[nH]c3ccccc3c1C2
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
23.20 | Ki | CHEMBL107420 | ChEMBL ↗ |
|
60744 ↗ |
c1cc2c(cc1OCCCOc1ccc3c(c1)[C@@]14CCCC[C@H]1[C@@H](C3)N(CC1CCC1)CC4)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
180.00 | Ki | CHEMBL1075629 | ChEMBL ↗ |
|
60747 ↗ |
Cc1cccc(O)c1C(=O)C1=CCCN2CCC[C@@H]12
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
94.00×103 | Ki | CHEMBL1076554 | ChEMBL ↗ |
|
60748 ↗ |
OC(COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
37.00 | Ki | CHEMBL1076572 | ChEMBL ↗ |
|
60749 ↗ |
OC(COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3)CC(O)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
33.00 | Ki | CHEMBL1076573 | ChEMBL ↗ |
|
60750 ↗ |
OC(CCC(O)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
420.00 | Ki | CHEMBL1076574 | ChEMBL ↗ |
|
60751 ↗ |
OC(CCCC(O)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
160.00 | Ki | CHEMBL1076575 | ChEMBL ↗ |
|
60752 ↗ |
OC(CCCCC(O)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
74.00 | Ki | CHEMBL1076576 | ChEMBL ↗ |
|
60753 ↗ |
OC(CCCCCC(O)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
99.00 | Ki | CHEMBL1076577 | ChEMBL ↗ |
|
60754 ↗ |
OC(CCCCCCC(O)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
27.00 | Ki | CHEMBL1076578 | ChEMBL ↗ |
|
60755 ↗ |
OC(COc1ccc(Cc2ccc(OCC(O)COc3ccc4c(c3)[C@@]35CCCC[C@H]3[C@@H](C4)N(CC3CCC3)CC5)cc2)cc1)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
29.00 | Ki | CHEMBL1076579 | ChEMBL ↗ |
|
60771 ↗ |
CNC(=O)Cn1c(=O)n(C2CCN([C@H]3CC[C@@H](C(C)C)CC3)CC2)c2ccccc21
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
7.00×103 | Ki | CHEMBL1080485 | ChEMBL ↗ |
|
60777 ↗ |
CCCCCCCCCC(=O)Oc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
20.00 | Ki | CHEMBL1080925 | ChEMBL ↗ |
|
60778 ↗ |
c1cc2c(cc1OCC1CO1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
200.00 | Ki | CHEMBL1081084 | ChEMBL ↗ |
|
60779 ↗ |
CCCCCCCCCCOc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
920.00 | Ki | CHEMBL1081093 | ChEMBL ↗ |
|
60782 ↗ |
CCCCCCCCC(O)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
52.00 | Ki | CHEMBL1081250 | ChEMBL ↗ |
|
60783 ↗ |
OC(COc1ccccc1)COc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CC1CCC1)CC3
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
86.00 | Ki | CHEMBL1081608 | ChEMBL ↗ |
|
60787 ↗ |
COc1ccc2c(c1O)[C@]13CCN(C)C(C2)[C@@]12C/C(=C\c1ccccc1)[C@@H]3c1[nH]c3ccccc3c1C2
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
15.90 | Ki | CHEMBL108608 | ChEMBL ↗ |
|
60800 ↗ |
COc1ccc2c(c1O)[C@]13CCN(C)C(C2)[C@]12CCC(=O)[C@H]3/C(=C/c1ccccc1)C2
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
5.50 | Ki | CHEMBL109040 | ChEMBL ↗ |
|
60808 ↗ |
COc1ccc2c(c1O)[C@]13CCN(C)C(C2)[C@]12CCC(=O)[C@H]3/C(=C(\C)c1ccccc1)C2
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
5.66 | Ki | CHEMBL110124 | ChEMBL ↗ |
|
60809 ↗ |
CN1CC[C@]23c4c5ccc(O)c4O[C@@]2(C)c2[nH]c4ccccc4c2C[C@@]3(C/C=C/c2ccccc2)C1C5
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
12.50 | Ki | CHEMBL110461 | ChEMBL ↗ |
|
60811 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)[C@@H](O)C/C=C/[C@@H](O)[C@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
230.00 | Ki | CHEMBL1161412 | ChEMBL ↗ |
|
60812 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)[C@H](O)C/C=C/[C@H](O)[C@@H](Cc1ccccc1)C(=O)NCCc1ccccc1
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
123.00 | Ki | CHEMBL1161413 | ChEMBL ↗ |
|
60813 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)[C@@H](O)C/C=C/[C@H](O)[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
CHEMBL236 ↗
UniProt: P41143 ↗ |
40.00 | Ki | CHEMBL1161414 | ChEMBL ↗ |