CHEMBL242 IC50
BioactivityChEMBL CHEMBL242 IC50 bioactivity data
1268 compounds · Target: Estrogen receptor beta ( CHEMBL242 ↗ ) · UniProt: Q92731 ↗ · IC50
Estrogen receptor beta, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
8388 ↗ |
COC(=O)CCCCCCC(=O)Nc1ccc(OS(=O)(=O)C2CC3OC2C(c2ccc(O)cc2)=C3c2ccc(O)cc2)cc1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
330.00 | IC50 | CHEMBL3589347 | ChEMBL ↗ |
|
8389 ↗ |
O=C(O)CCCCCCC(=O)Nc1ccc(OS(=O)(=O)C2CC3OC2C(c2ccc(O)cc2)=C3c2ccc(O)cc2)cc1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
160.00 | IC50 | CHEMBL3589349 | ChEMBL ↗ |
|
8390 ↗ |
O=C(CCCCCCC(=O)Nc1ccc(OS(=O)(=O)C2CC3OC2C(c2ccc(O)cc2)=C3c2ccc(O)cc2)cc1)NO
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
1.14×103 | IC50 | CHEMBL3589351 | ChEMBL ↗ |
|
8399 ↗ |
O=C(CCCCCCC(=O)Nc1ccc(C2=C(c3ccc(O)cc3)C3CC(S(=O)(=O)Oc4ccc5ccccc5c4)C2O3)cc1)NO
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
7.70×103 | IC50 | CHEMBL3589701 | ChEMBL ↗ |
|
9695 ↗ |
CN(c1ccccc1Cl)S(=O)(=O)C1CC2OC1C(c1ccc(NC(=O)CCCCCCC(=O)O)cc1)=C2c1ccc(O)cc1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
2.11×103 | IC50 | CHEMBL4855392 | ChEMBL ↗ |
|
10257 ↗ |
CC#C[C@@]1(O)CC[C@@]2(CC)c3ccc(O)cc3CC[C@@H]2C1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
580.00 | IC50 | CHEMBL10560 | ChEMBL ↗ |
|
10397 ↗ |
CCC[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
132.00 | IC50 | CHEMBL201517 | ChEMBL ↗ |
|
10398 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C\Cl)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
83.00 | IC50 | CHEMBL201569 | ChEMBL ↗ |
|
10399 ↗ |
CC#C[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
381.00 | IC50 | CHEMBL201809 | ChEMBL ↗ |
|
10400 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C\F)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
25.00 | IC50 | CHEMBL202007 | ChEMBL ↗ |
|
10401 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C/F)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
22.00 | IC50 | CHEMBL202400 | ChEMBL ↗ |
|
10402 ↗ |
C/C=C/[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
96.00 | IC50 | CHEMBL202415 | ChEMBL ↗ |
|
10405 ↗ |
C#CC[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
286.00 | IC50 | CHEMBL203561 | ChEMBL ↗ |
|
10406 ↗ |
C=C[C@]12CCC(=O)C=C1CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
782.00 | IC50 | CHEMBL203748 | ChEMBL ↗ |
|
10407 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C/Br)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
210.00 | IC50 | CHEMBL204317 | ChEMBL ↗ |
|
10408 ↗ |
CO/C=C/[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
1.30×103 | IC50 | CHEMBL204389 | ChEMBL ↗ |
|
10409 ↗ |
C=C[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@]2(C)O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
25.00 | IC50 | CHEMBL204642 | ChEMBL ↗ |
|
10544 ↗ |
CCC(CC)(c1ccc(N)c(C)c1)c1ccc(O)c(C)c1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
43.00 | IC50 | CHEMBL2403348 | ChEMBL ↗ |
|
10545 ↗ |
CC[Si](CC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
800.00 | IC50 | CHEMBL2403349 | ChEMBL ↗ |
|
10547 ↗ |
CCC(CC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
260.00 | IC50 | CHEMBL2403355 | ChEMBL ↗ |
|
10548 ↗ |
CCCC(CCC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
140.00 | IC50 | CHEMBL2403356 | ChEMBL ↗ |
|
10549 ↗ |
COc1cc(CNC(=O)[C@@]2(Cc3ccccc3)OC(=O)N([C@@H]3CCc4ccccc43)C2=O)cc(OC)c1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
15.00×103 | IC50 | CHEMBL2407647 | ChEMBL ↗ |
|
10703 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(-c4cc[nH]n4)ccc3[nH]2)C1=O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
2.60×103 | IC50 | CHEMBL3576885 | ChEMBL ↗ |
|
10704 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(Cl)ccc3[nH]2)C1=O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
2.40×103 | IC50 | CHEMBL3578271 | ChEMBL ↗ |
|
10705 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(C(F)(F)F)ccc3[nH]2)C1=O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
2.70×103 | IC50 | CHEMBL3578274 | ChEMBL ↗ |
|
10706 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(NS(C)(=O)=O)ccc3[nH]2)C1=O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
12.00×103 | IC50 | CHEMBL3578276 | ChEMBL ↗ |
|
10707 ↗ |
Cc1nocc1-c1ccc2[nH]c([C@@]3(Cc4ccccc4)OC(=O)N([C@H](C)c4ccc(F)cc4)C3=O)nc2c1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
3.00×103 | IC50 | CHEMBL3578284 | ChEMBL ↗ |
|
10708 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(N4CCOCC4)ccc3[nH]2)C1=O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
5.30×103 | IC50 | CHEMBL3578285 | ChEMBL ↗ |
|
10709 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3cc(-c4cccnc4)ccc3[nH]2)C1=O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
2.70×103 | IC50 | CHEMBL3578286 | ChEMBL ↗ |
|
10710 ↗ |
C[C@H](c1ccc(F)cc1)N1C(=O)O[C@](Cc2ccccc2)(c2nc3c(NS(C)(=O)=O)cccc3[nH]2)C1=O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
7.30×103 | IC50 | CHEMBL3578295 | ChEMBL ↗ |
|
10790 ↗ |
C=CC[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
128.00 | IC50 | CHEMBL369979 | ChEMBL ↗ |
|
10791 ↗ |
CC/C=C\[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
361.00 | IC50 | CHEMBL369991 | ChEMBL ↗ |
|
10792 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C/Cl)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
122.00 | IC50 | CHEMBL370236 | ChEMBL ↗ |
|
10793 ↗ |
C=C[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
11.00 | IC50 | CHEMBL373019 | ChEMBL ↗ |
|
10802 ↗ |
C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@@]43/C=C\Br)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
212.00 | IC50 | CHEMBL379441 | ChEMBL ↗ |
|
10803 ↗ |
CO/C=C\[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
303.00 | IC50 | CHEMBL380876 | ChEMBL ↗ |
|
10804 ↗ |
C#C[C@]1(O)CCC2C3CC=C4C[C@@H](O)CC[C@]4(C=C)C3CC[C@@]21C
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
14.00 | IC50 | CHEMBL381566 | ChEMBL ↗ |
|
10805 ↗ |
CC[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
16.00 | IC50 | CHEMBL382097 | ChEMBL ↗ |
|
10808 ↗ |
C/C=C\[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
16.00 | IC50 | CHEMBL383253 | ChEMBL ↗ |
|
10829 ↗ |
O=S(=O)(Nc1ccc(Oc2ccccc2)cc1)c1cccc(C(F)(F)F)c1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
23.00×103 | IC50 | CHEMBL3927163 | ChEMBL ↗ |
|
10918 ↗ |
CC(C)(c1ccc(O)cc1)c1ccc(O)cc1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
870.00 | IC50 | CHEMBL418971 | ChEMBL ↗ |
|
10955 ↗ |
C#C[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
17.00 | IC50 | CHEMBL437065 | ChEMBL ↗ |
|
10956 ↗ |
C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
9.95 | IC50 | CHEMBL440283 | ChEMBL ↗ |
|
16141 ↗ |
O=C1C[C@@H](c2ccc(O)cc2)Oc2cc(O)cc(O)c21
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
13.47×103 | IC50 | CHEMBL9352 | ChEMBL ↗ |
|
19476 ↗ |
O=C(/C=C/c1ccc(O)cc1)c1ccc(O)cc1O
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
269.00 | IC50 | CHEMBL129795 | ChEMBL ↗ |
|
20551 ↗ |
COc1ccc(CCCc2ccc(O)cc2)c(O)c1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
1.80×103 | IC50 | CHEMBL465879 | ChEMBL ↗ |
|
20608 ↗ |
CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
1.34 | IC50 | CHEMBL489 | ChEMBL ↗ |
|
31781 ↗ |
CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccc(O)cc1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
3.61 | IC50 | CHEMBL10041 | ChEMBL ↗ |
|
31782 ↗ |
Oc1ccc2c(c1)CCN(c1ccccc1)C2c1ccc(OCCN2CCCCC2)cc1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
317.50 | IC50 | CHEMBL101382 | ChEMBL ↗ |
|
31783 ↗ |
Oc1ccc2c(c1)CCN(c1ccccc1)C2c1ccc(F)cc1
|
CHEMBL242 ↗
UniProt: Q92731 ↗ |
421.00 | IC50 | CHEMBL103650 | ChEMBL ↗ |