CHEMBL253 Ki
BioactivityChEMBL CHEMBL253 Ki bioactivity data
3345 compounds · Target: Cannabinoid receptor 2 ( CHEMBL253 ↗ ) · UniProt: P34972 ↗ · Ki
Cannabinoid receptor 2, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
11612 ↗ |
CN(CCCCCCCOc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(-c3ccccc3)cc2)cc1)Cc1ccccc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
1.79×103 | Ki | CHEMBL2160219 | ChEMBL ↗ |
|
11615 ↗ |
CCN(CC)Cc1ccc(C(=O)c2c(-c3ccc(OCCCCCCCN(C)Cc4ccccc4)cc3)oc3ccccc23)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
1.12×103 | Ki | CHEMBL2160222 | ChEMBL ↗ |
|
11616 ↗ |
CCN(CC)CCOc1cccc(C(=O)c2c(-c3ccc(OCCCCCCCN(C)Cc4ccccc4)cc3)oc3ccccc23)c1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
690.00 | Ki | CHEMBL2160223 | ChEMBL ↗ |
|
11617 ↗ |
CCN(CC)CCOc1ccc(C(=O)c2c(-c3ccc(OCCCCCCCN(C)Cc4ccccc4)cc3)oc3ccccc23)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
1.18×103 | Ki | CHEMBL2160224 | ChEMBL ↗ |
|
11618 ↗ |
CN(CCCCCCCOc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(OCCN3CCOCC3)cc2)cc1)Cc1ccccc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
580.00 | Ki | CHEMBL2160225 | ChEMBL ↗ |
|
11816 ↗ |
COc1ccc(COc2nn(CCN(C(C)C)C(C)C)c3ccccc23)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
7.70×103 | Ki | CHEMBL3116280 | ChEMBL ↗ |
|
11817 ↗ |
CC(C)N(CCn1nc(OCc2cccc3ccccc23)c2ccccc21)C(C)C
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
5.40×103 | Ki | CHEMBL3116282 | ChEMBL ↗ |
|
11818 ↗ |
c1ccc2c(COc3nn(CCN4CCCC4)c4ccccc34)cccc2c1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
400.00 | Ki | CHEMBL3116283 | ChEMBL ↗ |
|
11819 ↗ |
c1ccc2c(COc3nn(CCN4CCCCC4)c4ccccc34)cccc2c1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
240.00 | Ki | CHEMBL3116284 | ChEMBL ↗ |
|
11820 ↗ |
c1ccc2cc(COc3nn(CCN4CCCCC4)c4ccccc34)ccc2c1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
2.00×103 | Ki | CHEMBL3116286 | ChEMBL ↗ |
|
11821 ↗ |
O=[N+]([O-])c1ccc2c(c1)c(OCc1cccc3ccccc13)nn2CCN1CCCC1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
130.00 | Ki | CHEMBL3116291 | ChEMBL ↗ |
|
11822 ↗ |
O=[N+]([O-])c1ccc2c(c1)c(OCc1ccc3ccccc3c1)nn2CCN1CCCCC1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
500.00 | Ki | CHEMBL3116294 | ChEMBL ↗ |
|
11823 ↗ |
Nc1ccc2c(c1)c(OCc1cccc3ccccc13)nn2CCN1CCCC1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
5.00×103 | Ki | CHEMBL3116299 | ChEMBL ↗ |
|
11824 ↗ |
Nc1ccc2c(c1)c(OCc1ccc3ccccc3c1)nn2CCN1CCCCC1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
2.00×103 | Ki | CHEMBL3116300 | ChEMBL ↗ |
|
11825 ↗ |
Brc1ccc2c(c1)c(OCc1ccc3ccccc3c1)nn2CCN1CCCCC1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
1.80×103 | Ki | CHEMBL3116301 | ChEMBL ↗ |
|
12428 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)NCCC(C)C)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
763.60 | Ki | CHEMBL4061358 | ChEMBL ↗ |
|
12470 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)Nc4ccccc4)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
14.40×103 | Ki | CHEMBL4076334 | ChEMBL ↗ |
|
12488 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCCCCCN2CCCCC2)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
1.00×103 | Ki | CHEMBL4082785 | ChEMBL ↗ |
|
12489 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCN2CCCCC2)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
188.00 | Ki | CHEMBL4082936 | ChEMBL ↗ |
|
12498 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCCCN2CCCCC2)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
4.80×103 | Ki | CHEMBL4085482 | ChEMBL ↗ |
|
12503 ↗ |
CCCCCCNC(=O)c1ccc2c(c1)nc(Cc1ccc(OCC)cc1)n2CCC(C)C
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
1.90×103 | Ki | CHEMBL4086412 | ChEMBL ↗ |
|
12530 ↗ |
CCOc1ccc(Nc2nc3cc(C(=O)N(CC)CC)ccc3n2CCN2CCCCC2)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
10.40×103 | Ki | CHEMBL4095946 | ChEMBL ↗ |
|
12552 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N4CCCCC4)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
384.50 | Ki | CHEMBL4104311 | ChEMBL ↗ |
|
12744 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)NCCCNc4c5c(nc6ccccc46)CCCC5)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
5.00×103 | Ki | CHEMBL4441666 | ChEMBL ↗ |
|
12747 ↗ |
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(NCc3ccc(F)cc3)cc2)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
20.00 | Ki | CHEMBL4442990 | ChEMBL ↗ |
|
12761 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)NCCSSCCNc4c5c(nc6ccccc46)CCCC5)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
6.80×103 | Ki | CHEMBL4447210 | ChEMBL ↗ |
|
12774 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)NCCCCCNc4c5c(nc6ccccc46)CCCC5)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
4.00×103 | Ki | CHEMBL4453905 | ChEMBL ↗ |
|
12775 ↗ |
CCCCCNc1ccc(C(=O)c2c(-c3ccc(OC)cc3)oc3ccccc23)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
70.00 | Ki | CHEMBL4454301 | ChEMBL ↗ |
|
12777 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCCCCCNc2c3c(nc4ccccc24)CCCC3)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
4.30×103 | Ki | CHEMBL4456083 | ChEMBL ↗ |
|
12778 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCOCCOCCNc2c3c(nc4ccccc24)CCCC3)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
28.70×103 | Ki | CHEMBL4456433 | ChEMBL ↗ |
|
12783 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCNc2c3c(nc4ccccc24)CCCC3)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
38.50 | Ki | CHEMBL4458217 | ChEMBL ↗ |
|
12787 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCCNc2c3c(nc4ccccc24)CCCC3)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
30.70×103 | Ki | CHEMBL4458929 | ChEMBL ↗ |
|
12793 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)NCCCCNc4c5c(nc6ccccc46)CCCC5)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
2.40×103 | Ki | CHEMBL4464883 | ChEMBL ↗ |
|
12813 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCCCNc2c3c(nc4ccccc24)CCCC3)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
26.90×103 | Ki | CHEMBL4473438 | ChEMBL ↗ |
|
12845 ↗ |
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(OCCCN(C)Cc3ccccc3)cc2)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
120.00 | Ki | CHEMBL4527727 | ChEMBL ↗ |
|
12870 ↗ |
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(N(Cc3ccc(F)cc3)Cc3ccc(F)cc3)cc2)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
430.00 | Ki | CHEMBL4543379 | ChEMBL ↗ |
|
12873 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CCCCNc4c5c(nc6ccccc46)CCCC5)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
3.00×103 | Ki | CHEMBL4545532 | ChEMBL ↗ |
|
12883 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)NCCOCCOCCNc4c5c(nc6ccccc46)CCCC5)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
17.40×103 | Ki | CHEMBL4555887 | ChEMBL ↗ |
|
12889 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)NCCCCCCNc4c5c(nc6ccccc46)CCCC5)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
9.60×103 | Ki | CHEMBL4558335 | ChEMBL ↗ |
|
12920 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCCCCNc2c3c(nc4ccccc24)CCCC3)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
7.30×103 | Ki | CHEMBL4583716 | ChEMBL ↗ |
|
12924 ↗ |
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(OCCN(C)Cc3ccccc3)cc2)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
690.00 | Ki | CHEMBL4587421 | ChEMBL ↗ |
|
12926 ↗ |
CCOc1ccc(Cc2nc3cc(C(=O)NCCNc4c5c(nc6ccccc46)CCCC5)ccc3n2CCC(C)C)cc1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
2.50×103 | Ki | CHEMBL4588547 | ChEMBL ↗ |
|
43615 ↗ |
O=C(C1CCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
2.12×103 | Ki | CHEMBL1076884 | ChEMBL ↗ |
|
43617 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)C1=NN(c2ccc(Cl)cc2)[C@@H](c2ccccc2)C1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
584.00 | Ki | CHEMBL1080156 | ChEMBL ↗ |
|
43619 ↗ |
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
305.00 | Ki | CHEMBL1080545 | ChEMBL ↗ |
|
43620 ↗ |
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)OCCO1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
200.00×10-3 | Ki | CHEMBL108085 | ChEMBL ↗ |
|
43625 ↗ |
CN/C(=N\S(=O)(=O)N1CCCCC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
3.50×103 | Ki | CHEMBL1081285 | ChEMBL ↗ |
|
43627 ↗ |
CN/C(=N\S(=O)(=O)c1cccc(Cl)c1)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccccc2)C1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
330.00 | Ki | CHEMBL1081304 | ChEMBL ↗ |
|
43628 ↗ |
CN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccccc2)C1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
248.00 | Ki | CHEMBL1081305 | ChEMBL ↗ |
|
43629 ↗ |
CN/C(=N\S(=O)(=O)c1ccc(C(F)(F)F)cc1)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccccc2)C1
|
CHEMBL253 ↗
UniProt: P34972 ↗ |
179.00 | Ki | CHEMBL1081306 | ChEMBL ↗ |