CHEMBL269 Ki
BioactivityChEMBL CHEMBL269 Ki bioactivity data
1141 compounds · Target: Delta-type opioid receptor ( CHEMBL269 ↗ ) · UniProt: P33533 ↗ · Ki
Delta-type opioid receptor, a molecular target studied in Rattus norvegicus.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
43532 ↗ |
CCC(=O)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
568.00 | Ki | CHEMBL596 | ChEMBL ↗ |
|
43586 ↗ |
CN(C)C(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
50.10 | Ki | CHEMBL841 | ChEMBL ↗ |
|
60832 ↗ |
Cc1cc(O)cc(C)c1C[C@@H](C(=O)N1Cc2ccccc2C[C@H]1C(=O)O)N(C)C
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
118.00×10-3 | Ki | CHEMBL1214049 | ChEMBL ↗ |
|
60835 ↗ |
CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
7.30 | Ki | CHEMBL13786 | ChEMBL ↗ |
|
60887 ↗ |
COC1Cc2ccccc2[C@]2(CC[C@@H](N(C)Cc3ccccc3)CC2)O1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
371.00 | Ki | CHEMBL1779999 | ChEMBL ↗ |
|
60888 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
600.00×10-3 | Ki | CHEMBL1782140 | ChEMBL ↗ |
|
60948 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](C)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
2.40 | Ki | CHEMBL1834247 | ChEMBL ↗ |
|
61018 ↗ |
NC(=O)[C@@H]1CC(=O)NCCCC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
170.86 | Ki | CHEMBL1927270 | ChEMBL ↗ |
|
61123 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CN(CC(=O)NCc2ccccc2)C1=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
11.00 | Ki | CHEMBL208683 | ChEMBL ↗ |
|
61226 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
1.49×103 | Ki | CHEMBL2181202 | ChEMBL ↗ |
|
61401 ↗ |
Cc1cc(O)cc(C)c1C[C@@H](C)CN1Cc2ccccc2C[C@H]1C(=O)NCC(=O)NCc1nc2ccccc2[nH]1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
58.00×10-3 | Ki | CHEMBL2375157 | ChEMBL ↗ |
|
61541 ↗ |
COc1c(O)ccc2c1[C@]13CCN(C)[C@H](C2)[C@]1(O)Cc1c([nH]c2ccccc12)C3
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
4.50 | Ki | CHEMBL246003 | ChEMBL ↗ |
|
61553 ↗ |
O=C1/C(=C/c2ccccc2)C[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
6.20 | Ki | CHEMBL252172 | ChEMBL ↗ |
|
61613 ↗ |
CN(C(=O)/C=C/c1ccoc1)[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
370.00×10-3 | Ki | CHEMBL267495 | ChEMBL ↗ |
|
61650 ↗ |
CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(=O)O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
9.64 | Ki | CHEMBL294616 | ChEMBL ↗ |
|
61653 ↗ |
C[C@H]1CN(CC[C@H](O)C2CCCCC2)CC[C@@]1(C)c1cccc(O)c1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
198.00 | Ki | CHEMBL300662 | ChEMBL ↗ |
|
61766 ↗ |
COC(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)[C@H]2[C@H]1CCC[C@@H]2N1CCCC1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
497.00 | Ki | CHEMBL3299005 | ChEMBL ↗ |
|
61780 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
99.20 | Ki | CHEMBL331325 | ChEMBL ↗ |
|
61862 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H]1Cc2ccccc2CN(CCC(N)=O)C1=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
17.00 | Ki | CHEMBL3408737 | ChEMBL ↗ |
|
61890 ↗ |
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
2.53 | Ki | CHEMBL35838 | ChEMBL ↗ |
|
61991 ↗ |
COC(=O)C1(NC(=O)C2=C(O)[C@@H]3Oc4c(O)ccc5c4[C@@]34CCN(CC3CC3)[C@H](C5)[C@]4(O)C2)CC1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
9.76 | Ki | CHEMBL3679612 | ChEMBL ↗ |
|
62080 ↗ |
C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCC(=O)Nc1ccccc1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
31.05 | Ki | CHEMBL3759092 | ChEMBL ↗ |
|
62158 ↗ |
Oc1cccc([C@]23CCC[C@H]([C@H]2O)N(CCc2ccccc2)CC3)c1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
19.20 | Ki | CHEMBL388873 | ChEMBL ↗ |
|
62453 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
5.30 | Ki | CHEMBL412923 | ChEMBL ↗ |
|
62753 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC(=O)NCc1ccccc1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
31.00×10-3 | Ki | CHEMBL458631 | ChEMBL ↗ |
|
62852 ↗ |
CCCCCCC(N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
1.76×103 | Ki | CHEMBL471806 | ChEMBL ↗ |
|
62978 ↗ |
NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCC(=O)N[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
6.32×103 | Ki | CHEMBL499141 | ChEMBL ↗ |
|
62982 ↗ |
CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
247.00 | Ki | CHEMBL500195 | ChEMBL ↗ |
|
62987 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC(=O)Nc1ccccc1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
42.00×10-3 | Ki | CHEMBL501451 | ChEMBL ↗ |
|
62993 ↗ |
CCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
2.94×103 | Ki | CHEMBL505502 | ChEMBL ↗ |
|
62994 ↗ |
CCCCCCCCCCC(N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
836.00 | Ki | CHEMBL505960 | ChEMBL ↗ |
|
63112 ↗ |
O=C1CC[C@@]2(OCCCc3ccccc3)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
410.00×10-3 | Ki | CHEMBL514774 | ChEMBL ↗ |
|
63211 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
118.00×10-3 | Ki | CHEMBL538700 | ChEMBL ↗ |
|
63314 ↗ |
CC(C)[C@@H](CN1CC[C@@](C)(c2cccc(O)c2)[C@@H](C)C1)NC(=O)[C@H]1Cc2ccc(O)cc2CN1C
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
616.00 | Ki | CHEMBL575508 | ChEMBL ↗ |
|
63338 ↗ |
NC(=O)[C@@H]1CSCSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
1.80 | Ki | CHEMBL583066 | ChEMBL ↗ |
|
63359 ↗ |
NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
19.20×103 | Ki | CHEMBL60444 | ChEMBL ↗ |
|
63369 ↗ |
CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(OCc2ccccc2)[C@H]1C5
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
2.14 | Ki | CHEMBL607351 | ChEMBL ↗ |
|
63378 ↗ |
COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)[C@@H](C2)N(C)CC[C@]314
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
787.00 | Ki | CHEMBL656 | ChEMBL ↗ |
|
63385 ↗ |
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
7.18 | Ki | CHEMBL8234 | ChEMBL ↗ |
|
63388 ↗ |
CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(O)[C@H]1C5
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
80.50 | Ki | CHEMBL963 | ChEMBL ↗ |
|
65125 ↗ |
C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
236.80 | Ki | CHEMBL278789 | ChEMBL ↗ |
|
65130 ↗ |
CO[C@@]12CCC(=O)[C@]3(C)Oc4c(O)ccc5c4[C@@]31CCN(C)[C@@H]2C5
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
13.30 | Ki | CHEMBL326684 | ChEMBL ↗ |
|
65132 ↗ |
NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
7.59×103 | Ki | CHEMBL333357 | ChEMBL ↗ |
|
65341 ↗ |
CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
480.00×10-3 | Ki | CHEMBL511142 | ChEMBL ↗ |
|
65492 ↗ |
C[C@H]1c2c(c3c(n2Cc2ccccc2)[C@@H]2Oc4c(O)ccc5c4[C@@]24CCN(C)[C@H](C5)[C@]4(O)C3)CC2(O)[C@H]3Cc4ccc(O)c(O)c4[C@@]12CCN3C
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
207.00 | Ki | CHEMBL2113073 | ChEMBL ↗ |
|
65493 ↗ |
Oc1ccc2c3c1O[C@H]1c4c(c5c(n4Cc4ccccc4)[C@@H]4Oc6c(O)ccc7c6[C@@]46CCN(CC4CC4)[C@H](C7)[C@]6(O)C5)C[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
8.60 | Ki | CHEMBL2113078 | ChEMBL ↗ |
|
65523 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCNc2ccc(CCc3ccccc3)cc21
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
8.90 | Ki | CHEMBL2322560 | ChEMBL ↗ |
|
65524 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCNc2ccc(Cc3cccc4ccccc34)cc21
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
6.00 | Ki | CHEMBL2322561 | ChEMBL ↗ |
|
65525 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCNc2ccc(Cc3ccc4ccccc4c3)cc21
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
10.00 | Ki | CHEMBL2322562 | ChEMBL ↗ |
|
65526 ↗ |
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCNc2ccc(CC3Cc4ccccc4C3)cc21
|
CHEMBL269 ↗
UniProt: P33533 ↗ |
4.10 | Ki | CHEMBL2322563 | ChEMBL ↗ |