CHEMBL302 Ki
BioactivityChEMBL CHEMBL302 Ki bioactivity data
1055 compounds · Target: Adenosine receptor A2a ( CHEMBL302 ↗ ) · UniProt: P30543 ↗ · Ki
Adenosine receptor A2a, a molecular target studied in Rattus norvegicus.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
14334 ↗ |
Cn1c(=O)c2c(nc(OCc3ccc(Cl)cc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
3.31×103 | Ki | CHEMBL1806759 | ChEMBL ↗ |
|
14420 ↗ |
Cn1c(=O)c2c(nc(SCc3ccccc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
4.64×103 | Ki | CHEMBL1927666 | ChEMBL ↗ |
|
14423 ↗ |
Cn1c(=O)c2c(nc(SCc3ccc(Cl)cc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
51.43×103 | Ki | CHEMBL1927669 | ChEMBL ↗ |
|
14541 ↗ |
Cn1c(=O)c2c(nc(COc3ccccc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
2.37×103 | Ki | CHEMBL2088299 | ChEMBL ↗ |
|
14546 ↗ |
Cn1c(=O)c2c(nc(COc3ccc(Cl)cc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.14×103 | Ki | CHEMBL2088306 | ChEMBL ↗ |
|
14547 ↗ |
Cn1c(=O)c2c(nc(COc3ccc(Br)cc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.73×103 | Ki | CHEMBL2088307 | ChEMBL ↗ |
|
14548 ↗ |
Cn1c(=O)c2c(nc(COc3ccc(F)cc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
2.57×103 | Ki | CHEMBL2088308 | ChEMBL ↗ |
|
14549 ↗ |
Cn1c(=O)c2c(nc(CSc3ccccc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
3.33×103 | Ki | CHEMBL2088309 | ChEMBL ↗ |
|
14556 ↗ |
Cn1c(=O)c2c(nc(CSc3ccc(Cl)cc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.50×103 | Ki | CHEMBL2088316 | ChEMBL ↗ |
|
16120 ↗ |
Cn1c(=O)c2c(nc(OCc3ccccc3)n2C)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
4.30×103 | Ki | CHEMBL602259 | ChEMBL ↗ |
|
23509 ↗ |
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
30.00 | Ki | CHEMBL477 | ChEMBL ↗ |
|
24387 ↗ |
O=C(CCc1ccccc1)Nc1nc2ccccc2c(=O)s1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
103.00 | Ki | CHEMBL2380385 | ChEMBL ↗ |
|
24388 ↗ |
COc1cccc(CCC(=O)Nc2nc3ccccc3c(=O)s2)c1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
294.00 | Ki | CHEMBL2380386 | ChEMBL ↗ |
|
24389 ↗ |
Cc1ccc2nc(NC(=O)CCCc3ccccc3)sc(=O)c2c1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
6.06×103 | Ki | CHEMBL2382420 | ChEMBL ↗ |
|
24392 ↗ |
O=C(CCCc1ccccc1)Nc1nc2sccc2c(=O)s1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
693.00 | Ki | CHEMBL2382425 | ChEMBL ↗ |
|
24394 ↗ |
O=C(CCc1ccccc1F)Nc1nc2ccccc2c(=O)s1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
2.19×103 | Ki | CHEMBL2382428 | ChEMBL ↗ |
|
24397 ↗ |
COc1cccc(/C=C/C(=O)Nc2nc3ccccc3c(=O)s2)c1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
253.00 | Ki | CHEMBL2382431 | ChEMBL ↗ |
|
24399 ↗ |
COc1cccc(C#CC(=O)Nc2nc3ccccc3c(=O)s2)c1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.72×103 | Ki | CHEMBL2382433 | ChEMBL ↗ |
|
24400 ↗ |
O=C(CCCc1ccccc1)Nc1nc2ccccc2c(=O)s1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
423.00 | Ki | CHEMBL2382434 | ChEMBL ↗ |
|
24401 ↗ |
COc1cccc(CCCC(=O)Nc2nc3ccccc3c(=O)s2)c1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
558.00 | Ki | CHEMBL2382435 | ChEMBL ↗ |
|
24403 ↗ |
O=C(C/C=C/c1ccccc1)Nc1nc2ccccc2c(=O)s1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
814.00 | Ki | CHEMBL2382438 | ChEMBL ↗ |
|
24404 ↗ |
COc1cccc(/C=C/CC(=O)Nc2nc3ccccc3c(=O)s2)c1
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
317.00 | Ki | CHEMBL2382439 | ChEMBL ↗ |
|
24405 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3CCc2ccc(Cl)cc2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
497.50 | Ki | CHEMBL239230 | ChEMBL ↗ |
|
24417 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3Cc2ccc(Cl)cc2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
5.75×103 | Ki | CHEMBL241617 | ChEMBL ↗ |
|
24418 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3Cc2cccc(Cl)c2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
961.00 | Ki | CHEMBL241618 | ChEMBL ↗ |
|
24470 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3CC(=O)N2CCN(Cc3ccccc3)CC2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
14.00×103 | Ki | CHEMBL3093214 | ChEMBL ↗ |
|
24474 ↗ |
CCCn1c(=O)c2c(nc3n2CCCN3CC(=O)N2CCN(Cc3ccc(C(F)(F)F)cc3)CC2)n(CCC)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
7.31×103 | Ki | CHEMBL3093221 | ChEMBL ↗ |
|
24476 ↗ |
CCn1c(=O)c2c(nc3n2CCCN3c2cccc(OC)c2)n(CC)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
5.37×103 | Ki | CHEMBL3093224 | ChEMBL ↗ |
|
24477 ↗ |
CCn1c(=O)c2c(nc3n2CCCN3CCc2ccccc2OC)n(CC)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.83×103 | Ki | CHEMBL3093225 | ChEMBL ↗ |
|
24478 ↗ |
CCn1c(=O)c2c(nc3n2CCCN3CCc2ccc(OC)cc2)n(CC)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
624.00 | Ki | CHEMBL3093227 | ChEMBL ↗ |
|
24479 ↗ |
CCn1c(=O)c2c(nc3n2CCCN3CCc2ccc(OC)c(OC)c2)n(CC)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.88×103 | Ki | CHEMBL3093228 | ChEMBL ↗ |
|
24480 ↗ |
CCn1c(=O)c2c(nc3n2CCCN3C2CCCCC2)n(CC)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.70×103 | Ki | CHEMBL3093230 | ChEMBL ↗ |
|
24481 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3c2cccc(Cl)c2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
3.76×103 | Ki | CHEMBL3093232 | ChEMBL ↗ |
|
24482 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3c2ccc(Cl)cc2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.21×103 | Ki | CHEMBL3093233 | ChEMBL ↗ |
|
24483 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3c2ccc(Cl)c(Cl)c2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
4.70×103 | Ki | CHEMBL3093234 | ChEMBL ↗ |
|
24484 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3Cc2ccc(Cl)c(Cl)c2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
3.69×103 | Ki | CHEMBL3093236 | ChEMBL ↗ |
|
24485 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3Cc2cc(Cl)cc(Cl)c2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.64×103 | Ki | CHEMBL3093237 | ChEMBL ↗ |
|
24486 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3CCc2cccc(Cl)c2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
166.00 | Ki | CHEMBL3093238 | ChEMBL ↗ |
|
24487 ↗ |
Cn1c(=O)c2c(nc3n2CCCN3CCc2ccc(Cl)c(Cl)c2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
780.00 | Ki | CHEMBL3093239 | ChEMBL ↗ |
|
24490 ↗ |
C#CCn1c(=O)c2c(nc3n2CCCN3Cc2ccccc2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
533.00 | Ki | CHEMBL3093310 | ChEMBL ↗ |
|
24491 ↗ |
C#CCn1c(=O)c2c(nc3n2CCCN3Cc2ccccc2OC)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
641.00 | Ki | CHEMBL3093311 | ChEMBL ↗ |
|
24492 ↗ |
C#CCn1c(=O)c2c(nc3n2CCCN3Cc2cccc(OC)c2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
696.00 | Ki | CHEMBL3093312 | ChEMBL ↗ |
|
24493 ↗ |
C#CCn1c(=O)c2c(nc3n2CCCN3Cc2ccc(OC)cc2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
3.03×103 | Ki | CHEMBL3093313 | ChEMBL ↗ |
|
24494 ↗ |
C#CCn1c(=O)c2c(nc3n2CCCN3Cc2cccs2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
259.00 | Ki | CHEMBL3093315 | ChEMBL ↗ |
|
24495 ↗ |
CCn1c(=O)c2c(nc3n2CCCN3c2ccc(F)cc2)n(CC)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.88×103 | Ki | CHEMBL3093325 | ChEMBL ↗ |
|
24496 ↗ |
CCn1c(=O)c2c(nc3n2CCCN3c2ccc(O)cc2)n(CC)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
896.50 | Ki | CHEMBL3093326 | ChEMBL ↗ |
|
24497 ↗ |
C#CCn1c(=O)c2c(nc3n2CCCN3c2cccc(Br)c2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
932.00 | Ki | CHEMBL3093331 | ChEMBL ↗ |
|
24498 ↗ |
C#CCn1c(=O)c2c(nc3n2CCCN3c2ccc(C(C)C)cc2)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
1.48×103 | Ki | CHEMBL3093333 | ChEMBL ↗ |
|
25124 ↗ |
Cn1c(=O)c2c(nc3n2CCN(c2cccc(Cl)c2)C3)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
557.00 | Ki | CHEMBL4442891 | ChEMBL ↗ |
|
25129 ↗ |
Cn1c(=O)c2c(nc3n2CCN(c2ccccc2)C3)n(C)c1=O
|
CHEMBL302 ↗
UniProt: P30543 ↗ |
3.83×103 | Ki | CHEMBL4444119 | ChEMBL ↗ |