CHEMBL3229 IC50
BioactivityChEMBL CHEMBL3229 IC50 bioactivity data
1331 compounds · Target: Fatty-acid amide hydrolase 1 ( CHEMBL3229 ↗ ) · UniProt: P97612 ↗ · IC50
Fatty-acid amide hydrolase 1, a molecular target studied in Rattus norvegicus.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
11570 ↗ |
CNC(=O)Oc1cccc(CN(C)CCCCCCCOc2ccc(-c3cc4ccccc4oc3=O)cc2)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
9.20×103 | IC50 | CHEMBL2047525 | ChEMBL ↗ |
|
11574 ↗ |
CN(CCCOc1ccc2c(=O)c3cccnc3oc2c1)Cc1cccc(OC(=O)NCCCCCCCN2CCOCC2)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
3.51×103 | IC50 | CHEMBL2047531 | ChEMBL ↗ |
|
12269 ↗ |
CN(CCCOc1ccc2c3c(c(=O)oc2c1)CCCC3)Cc1cccc(OC(=O)NCCCCCc2ccccc2)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
2.44×103 | IC50 | CHEMBL3827734 | ChEMBL ↗ |
|
13623 ↗ |
CN(CCCOc1ccc2ccc(=O)oc2c1)Cc1cccc(OC(=O)NC2CCCC2)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
2.53 | IC50 | CHEMBL5218447 | ChEMBL ↗ |
|
13637 ↗ |
CN(CCCOc1ccc2ccc(=O)oc2c1)Cc1cccc(OC(=O)NC2CCCCC2)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
1.33 | IC50 | CHEMBL5220375 | ChEMBL ↗ |
|
27402 ↗ |
OB(O)CCc1ccccc1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
1.30×103 | IC50 | CHEMBL20461 | ChEMBL ↗ |
|
27527 ↗ |
COc1ccc(B(O)O)cc1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
2.00×103 | IC50 | CHEMBL21427 | ChEMBL ↗ |
|
30271 ↗ |
OB(O)/C=C/c1ccc(-c2ccccc2)cc1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
14.00 | IC50 | CHEMBL453758 | ChEMBL ↗ |
|
31621 ↗ |
CC(C)c1cccc(C(C)C)c1O
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
14.00×103 | IC50 | CHEMBL526 | ChEMBL ↗ |
|
43747 ↗ |
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
11.75×103 | IC50 | CHEMBL15848 | ChEMBL ↗ |
|
43809 ↗ |
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
10.00 | IC50 | CHEMBL175247 | ChEMBL ↗ |
|
43914 ↗ |
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1O
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
53.20×103 | IC50 | CHEMBL190461 | ChEMBL ↗ |
|
43988 ↗ |
CN(Cc1ccccc1)C(=O)N1CC(O[C@H](c2ccc(Cl)cc2)c2cccnc2Cl)C1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
4.53×103 | IC50 | CHEMBL1952279 | ChEMBL ↗ |
|
43989 ↗ |
CN(Cc1ccccc1)C(=O)N1CC(O[C@@H](c2ccc(Cl)cc2)c2cccnc2Cl)C1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
94.00 | IC50 | CHEMBL1952280 | ChEMBL ↗ |
|
44332 ↗ |
CCCCCCc1ccc(O)cc1OCCCCCCCCCCC(=O)Nc1ccc(O)cc1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
18.00×103 | IC50 | CHEMBL223223 | ChEMBL ↗ |
|
44355 ↗ |
CCCCCc1cc(O)cc(OCCCCCCCCCCC(=O)NCc2ccc(OC)c(O)c2)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
10.00×103 | IC50 | CHEMBL228403 | ChEMBL ↗ |
|
44357 ↗ |
CCCCCc1cc(O)cc(OCCCCCCCCCCCC(=O)NC2CC2)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
50.00×103 | IC50 | CHEMBL228405 | ChEMBL ↗ |
|
44358 ↗ |
CCCCCCc1c(O)cccc1OCCCCCCCC(=O)NCCO
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
25.00×103 | IC50 | CHEMBL228455 | ChEMBL ↗ |
|
44359 ↗ |
CCCCCCc1c(O)cccc1OCCCCCCCC(=O)NC1CC1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
50.00×103 | IC50 | CHEMBL228456 | ChEMBL ↗ |
|
44362 ↗ |
CCCCCCc1c(O)cccc1OCCCCCCCCCCCC(=O)NCCO
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
50.00×103 | IC50 | CHEMBL228508 | ChEMBL ↗ |
|
44363 ↗ |
CCCCCCc1ccc(OCCCCCCCC(=O)NCCO)cc1O
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
50.00×103 | IC50 | CHEMBL228509 | ChEMBL ↗ |
|
44976 ↗ |
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCc1ccc(OC)cc1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
2.75×103 | IC50 | CHEMBL371881 | ChEMBL ↗ |
|
45057 ↗ |
CCCCCCc1c(O)cccc1OCCCCCCCCCCC(=O)NCc1ccc(OC)c(O)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
50.00×103 | IC50 | CHEMBL388393 | ChEMBL ↗ |
|
45667 ↗ |
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H](NC(C)=O)C(C)CC
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
6.60×103 | IC50 | CHEMBL484215 | ChEMBL ↗ |
|
45668 ↗ |
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H]1CCCN1C=O
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
3.40×103 | IC50 | CHEMBL484392 | ChEMBL ↗ |
|
45910 ↗ |
O=C(N1CCCCC1)N1CC(O[C@H](c2ccc(Cl)cc2)c2cccnc2Cl)C1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
42.00×103 | IC50 | CHEMBL558709 | ChEMBL ↗ |
|
47581 ↗ |
CCCCNC(=O)Oc1cccc(CN(C)CCCOc2ccc3ccc(=O)oc3c2)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
8.68×103 | IC50 | CHEMBL128551 | ChEMBL ↗ |
|
47956 ↗ |
CN(C)C(=O)[C@H]1C[C@@H]1c1ccc(-c2ncn(C)c2Sc2ccc(Cl)cn2)cc1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
1.70 | IC50 | CHEMBL2386558 | ChEMBL ↗ |
|
49132 ↗ |
CC(C)Cc1ccc(C(C)C(=O)O)cc1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
261.51×103 | IC50 | CHEMBL521 | ChEMBL ↗ |
|
51505 ↗ |
O=C(Nc1cccnn1)N1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
6.55 | IC50 | CHEMBL1651534 | ChEMBL ↗ |
|
52317 ↗ |
COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
77.00 | IC50 | CHEMBL1079421 | ChEMBL ↗ |
|
52319 ↗ |
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCP(=O)(F)OC
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
23.00 | IC50 | CHEMBL113262 | ChEMBL ↗ |
|
52339 ↗ |
O=C(Nc1cccnc1)N1CCC(Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
11.50 | IC50 | CHEMBL1651524 | ChEMBL ↗ |
|
52342 ↗ |
O=C(CCCCCc1ccccc1)c1nc2ncccc2o1
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
3.45 | IC50 | CHEMBL175854 | ChEMBL ↗ |
|
52343 ↗ |
O=C(Nc1ccccc1F)N1CCC2(CC1)OCc1cc(Br)ccc1O2
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
36.00 | IC50 | CHEMBL1761279 | ChEMBL ↗ |
|
52344 ↗ |
Cn1c(=O)n(C2CCCN(c3nccc(-c4cc5ccccc5o4)n3)C2)c2ccccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
780.00 | IC50 | CHEMBL1761281 | ChEMBL ↗ |
|
52346 ↗ |
CCn1c(=O)n([C@@H]2CCCN(c3nccc(-c4cc5ccccc5o4)n3)C2)c2ncccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
10.00 | IC50 | CHEMBL1761284 | ChEMBL ↗ |
|
52349 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3ccnc(-c4cc5ccccc5o4)n3)C2)c2ccccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
300.00 | IC50 | CHEMBL1761289 | ChEMBL ↗ |
|
52350 ↗ |
CCn1c(=O)n(C2CCCN(c3cc(-c4cc5ccccc5o4)ncn3)C2)c2ncccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
570.00 | IC50 | CHEMBL1761290 | ChEMBL ↗ |
|
52351 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3cc(-c4cc5ccccc5o4)nc(N)n3)C2)c2ncccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
200.00 | IC50 | CHEMBL1761291 | ChEMBL ↗ |
|
52352 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3nccc(-c4ccccc4)n3)C2)c2ncccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
220.00 | IC50 | CHEMBL1761292 | ChEMBL ↗ |
|
52353 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3ccnc(-c4ccccc4F)n3)C2)c2ccccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
3.00×103 | IC50 | CHEMBL1761293 | ChEMBL ↗ |
|
52354 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3ccnc(-c4cccc(F)c4)n3)C2)c2ccccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
1.20×103 | IC50 | CHEMBL1761294 | ChEMBL ↗ |
|
52355 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3ccnc(-c4ccc(F)cc4)n3)C2)c2ccccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
120.00 | IC50 | CHEMBL1761295 | ChEMBL ↗ |
|
52356 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3ccnc(-c4ccc(Cl)cc4)n3)C2)c2ccccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
160.00 | IC50 | CHEMBL1761296 | ChEMBL ↗ |
|
52357 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3ccnc(-c4ccc(C)cc4)n3)C2)c2ccccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
280.00 | IC50 | CHEMBL1761297 | ChEMBL ↗ |
|
52358 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3ccnc(-c4ccc(Cl)s4)n3)C2)c2ccccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
340.00 | IC50 | CHEMBL1761298 | ChEMBL ↗ |
|
52359 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3nccc(-c4ccc(F)cc4)n3)C2)c2ncccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
30.00 | IC50 | CHEMBL1761299 | ChEMBL ↗ |
|
52360 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3nccc(-c4cccs4)n3)C2)c2ncccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
190.00 | IC50 | CHEMBL1761300 | ChEMBL ↗ |
|
52361 ↗ |
CCn1c(=O)n([C@H]2CCCN(c3nccc(-c4ccc(Cl)s4)n3)C2)c2ncccc21
|
CHEMBL3229 ↗
UniProt: P97612 ↗ |
4.00 | IC50 | CHEMBL1761301 | ChEMBL ↗ |