CHEMBL3242 Ki
BioactivityChEMBL CHEMBL3242 Ki bioactivity data
3684 compounds · Target: Carbonic anhydrase 12 ( CHEMBL3242 ↗ ) · UniProt: O43570 ↗ · Ki
Carbonic anhydrase 12, a molecular target studied in Homo sapiens.
| ID ↑ | SMILES | Target | Activity (nM) | Type | Ref | Link | |
|---|---|---|---|---|---|---|---|
|
1833 ↗ |
Cn1c(=O)ccc2ccccc21
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
83.50 | Ki | CHEMBL216146 | ChEMBL ↗ |
|
6570 ↗ |
O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.12×103 | Ki | CHEMBL6246 | ChEMBL ↗ |
|
6574 ↗ |
Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1Nc1nccc(-c2cccnc2)n1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
980.00 | Ki | CHEMBL941 | ChEMBL ↗ |
|
6594 ↗ |
O=C(NO)c1ccccc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.51×103 | Ki | CHEMBL16300 | ChEMBL ↗ |
|
6753 ↗ |
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
5.87×103 | Ki | CHEMBL325041 | ChEMBL ↗ |
|
8041 ↗ |
Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
18.00 | Ki | CHEMBL118 | ChEMBL ↗ |
|
10445 ↗ |
CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
3.25 | Ki | CHEMBL218490 | ChEMBL ↗ |
|
11601 ↗ |
Nc1ccc(S(N)(=O)=O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
37.00 | Ki | CHEMBL21 | ChEMBL ↗ |
|
11815 ↗ |
O=C1NS(=O)(=O)c2ccccc21
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
641.50 | Ki | CHEMBL310671 | ChEMBL ↗ |
|
13340 ↗ |
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.39×103 | Ki | CHEMBL50 | ChEMBL ↗ |
|
14315 ↗ |
Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
950.00 | Ki | CHEMBL165 | ChEMBL ↗ |
|
14767 ↗ |
O=c1c(O)c(-c2ccccc2)oc2cc(O)cc(O)c12
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
41.80 | Ki | CHEMBL309490 | ChEMBL ↗ |
|
14781 ↗ |
C#CCCCOc1ccc2ccc(=O)oc2c1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
370.00 | Ki | CHEMBL3121782 | ChEMBL ↗ |
|
16141 ↗ |
O=C1C[C@@H](c2ccc(O)cc2)Oc2cc(O)cc(O)c21
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
44.30 | Ki | CHEMBL9352 | ChEMBL ↗ |
|
17675 ↗ |
O=c1c(O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
145.90 | Ki | CHEMBL150 | ChEMBL ↗ |
|
17678 ↗ |
O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
60.30 | Ki | CHEMBL151 | ChEMBL ↗ |
|
17957 ↗ |
Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
302.00 | Ki | CHEMBL255863 | ChEMBL ↗ |
|
19946 ↗ |
O=c1cc(-c2ccccc2)oc2ccccc12
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
7.28×103 | Ki | CHEMBL275638 | ChEMBL ↗ |
|
19948 ↗ |
O=c1cc(-c2ccccc2)oc2cc(O)ccc12
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
8.46×103 | Ki | CHEMBL276915 | ChEMBL ↗ |
|
19961 ↗ |
NS(=O)(=O)Oc1ccc2c3c(c(=O)oc2c1)CCCCC3
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
12.00 | Ki | CHEMBL286738 | ChEMBL ↗ |
|
20840 ↗ |
COc1cc(/C=C/C(=O)/C=C(O)/C=C/c2ccc(O)c(OC)c2)ccc1O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
3.48×103 | Ki | CHEMBL116438 | ChEMBL ↗ |
|
20908 ↗ |
O=C(O)/C=C/c1ccc(O)c(O)c1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.06×103 | Ki | CHEMBL145 | ChEMBL ↗ |
|
24093 ↗ |
Cc1cc(=O)oc2cc(O)ccc12
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
8.10×103 | Ki | CHEMBL12208 | ChEMBL ↗ |
|
24164 ↗ |
O=c1ccc2ccc(OCc3ccccc3)cc2o1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
6.50×103 | Ki | CHEMBL145781 | ChEMBL ↗ |
|
24170 ↗ |
CC(=O)c1cc2ccccc2oc1=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
7.80 | Ki | CHEMBL149463 | ChEMBL ↗ |
|
25674 ↗ |
CCOC(=O)c1cc2ccc(OC)cc2oc1=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
8.80×103 | Ki | CHEMBL568385 | ChEMBL ↗ |
|
25679 ↗ |
Cc1ccc2oc(=O)c(C(=O)O)cc2c1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
8.00×103 | Ki | CHEMBL577123 | ChEMBL ↗ |
|
25717 ↗ |
O=C(O)c1cc2ccccc2oc1=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
2.90×103 | Ki | CHEMBL83294 | ChEMBL ↗ |
|
26746 ↗ |
NS(=O)(=O)c1cc2c(cc1Cl)NC(C(Cl)Cl)NS2(=O)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
312.00 | Ki | CHEMBL1054 | ChEMBL ↗ |
|
26747 ↗ |
NS(=O)(=O)c1cc(C2(O)NC(=O)c3ccccc32)ccc1Cl
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
4.50 | Ki | CHEMBL1055 | ChEMBL ↗ |
|
26773 ↗ |
NS(=O)(=O)c1ccc(CNS(=O)(=O)[C@@H]2O[C@H](C(=O)O)[C@H](O)[C@H](O)[C@H]2O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
8.90 | Ki | CHEMBL1088997 | ChEMBL ↗ |
|
26774 ↗ |
NS(=O)(=O)c1ccc(CNS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
8.90 | Ki | CHEMBL1088998 | ChEMBL ↗ |
|
26775 ↗ |
CC(=O)OC[C@H]1O[C@@H](SNCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
11.50 | Ki | CHEMBL1089015 | ChEMBL ↗ |
|
26776 ↗ |
NS(=O)(=O)c1ccc(CNS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
8.20 | Ki | CHEMBL1089329 | ChEMBL ↗ |
|
26777 ↗ |
COC(=O)[C@H]1O[C@@H](S(=O)(=O)NCCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.70 | Ki | CHEMBL1089370 | ChEMBL ↗ |
|
26778 ↗ |
NS(=O)(=O)c1ccc(CCNS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
7.60 | Ki | CHEMBL1089371 | ChEMBL ↗ |
|
26779 ↗ |
NS(=O)(=O)c1ccc(CCNS(=O)(=O)[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
7.80 | Ki | CHEMBL1089372 | ChEMBL ↗ |
|
26783 ↗ |
NS(=O)(=O)c1ccc(CCNS(=O)(=O)[C@@H]2O[C@H](C(=O)O)[C@H](O)[C@H](O)[C@H]2O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.50 | Ki | CHEMBL1090010 | ChEMBL ↗ |
|
26784 ↗ |
NS(=O)(=O)c1ccc(CCNS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.10 | Ki | CHEMBL1090011 | ChEMBL ↗ |
|
26785 ↗ |
NS(=O)(=O)c1ccc(CCNS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
7.30 | Ki | CHEMBL1090012 | ChEMBL ↗ |
|
26786 ↗ |
CC(=O)OC[C@H]1O[C@@H](S(=O)(=O)NCCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.50 | Ki | CHEMBL1090030 | ChEMBL ↗ |
|
26790 ↗ |
CC(=O)OC[C@H]1O[C@@H](S(=O)(=O)NCCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.40 | Ki | CHEMBL1091073 | ChEMBL ↗ |
|
26791 ↗ |
CC(=O)OC[C@H]1O[C@@H](O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](SNCc3ccc(S(N)(=O)=O)cc3)O[C@@H]2COC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.80 | Ki | CHEMBL1091318 | ChEMBL ↗ |
|
26792 ↗ |
CC(=O)OC[C@H]1O[C@@H](SNCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1O[C@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
8.50 | Ki | CHEMBL1091319 | ChEMBL ↗ |
|
26793 ↗ |
CC(=O)OC[C@H]1O[C@@H](SNCCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
13.60 | Ki | CHEMBL1091779 | ChEMBL ↗ |
|
26794 ↗ |
CC(=O)OC[C@H]1O[C@@H](SNCCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
16.70 | Ki | CHEMBL1091780 | ChEMBL ↗ |
|
26795 ↗ |
COC(=O)[C@H]1O[C@@H](SNCCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.50 | Ki | CHEMBL1091781 | ChEMBL ↗ |
|
26796 ↗ |
NS(=O)(=O)c1ccc(CNS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
8.30 | Ki | CHEMBL1091806 | ChEMBL ↗ |
|
26797 ↗ |
CC(=O)OC[C@H]1O[C@@H](O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](S(=O)(=O)NCc3ccc(S(N)(=O)=O)cc3)O[C@@H]2COC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
10.40 | Ki | CHEMBL1092027 | ChEMBL ↗ |
|
26798 ↗ |
CC(=O)OC[C@H]1O[C@@H](S(=O)(=O)NCc2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1O[C@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O
|
CHEMBL3242 ↗
UniProt: O43570 ↗ |
9.10 | Ki | CHEMBL1092028 | ChEMBL ↗ |